Results 91 to 100 of about 3,009,034 (256)
Dual-task interference: Attentional and neurophysiological influences
Performing two tasks simultaneously often degrades performance of one or both tasks. While this dual-task interference is classically interpreted in terms of shared attentional resources, where two motor tasks are performed simultaneously interactions ...
Jeffery Summers (14750413) +3 more
core
Background The purpose of this study was to examine task-related changes in prefrontal cortex (PFC) activity during a dual-task in both healthy young and older adults and compare patterns of activation between the age groups.
Ohsugi Hironori +3 more
doaj +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Illinois Terrorism Task Force- 2004 Annual Report [PDF]
This report documents the activities and accomplishments of the Illinois Terrorism Task Force during the year 2004.Submitted by Adam Groves (agroves@fsi.uiuc.edu) on 2006-09-22T16:01:23Z No.
Illinois Terrorism Task Force
core
Age-dependent gait characteristics and associations with cognition, motor behavior, injuries, and psychosocial functioning were investigated in 138 typically developing children aged 6.7 to 13.2 years (M =10.0 years).
Priska eHagmann-von Arx +3 more
doaj +1 more source
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Illinois Terrorism Task Force- 2007 Annual Report [PDF]
This report documents the activities and accomplishments of the Illinois Terrorism Task Force during the year 2007.not peer reviewedSubmitted by Adam Groves (agroves@fsi.uiuc.edu) on 2008-07-03T15:32:48Z No. of bitstreams: 1 Illinois Terrorism Task Force-
Illinois Terrorism Task Force
core
CEACAM1 participation in breast cancer progression
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Burciu, RoxanaBackground: People often use both hands simultaneously to accomplish everyday tasks, and occasionally they do so while also attending to a cognitive task.
Crisomia, Sophia
core +1 more source

