Results 161 to 170 of about 103,825 (319)

Canonical Duality Theory for Solving Non-monotone Variational Inequality Problems

open access: yes, 2017
This paper presents a canonical dual approach for solving a class of non-monotone variational inequality problems. It shows that by using the canonical dual transformation, these challenging problems can be reformulated as a canonical dual problem, which
Shouyang Wang   +5 more
core   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

AN EXAMINATION OF THE EMPIRICAL PROPERTIES OF DUALITY BETWEEN THE RESTRICTED PROFIT, UNRESTRICTED PROFIT, AND PRODUCTION FUNCTIONS

open access: yes
This research examines the empirical properties of duality theory. A comparison of the Hessian matrices calculated from the normalized unrestricted and restricted profit, and production functions indicate that duality is highly sensitive to measurement ...
Abdulkadri, Abdullahi O.   +2 more
core  

Aspects of gauge/string theory duality: BMN correspondence and MHV rules [PDF]

open access: yes, 2007
One of the most striking examples of duality correspondence between gauge theories and string theories is the AdS/CFT duality. It relates the type IIB superstring theory on AdS5 x 5 5 to 4-dimensional N = 4 Yangs Mills in its superconformal phase ...
Georgiou, George
core  

Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10

open access: yesFEBS Open Bio, EarlyView.
Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee   +6 more
wiley   +1 more source

The Benefit Function Approach to Modeling Price-Dependent Demand Systems: An Application of Duality Theory [PDF]

open access: yes
In this article we advocate more extensive use of the benefit function in specifying price-dependent or inverse demand models. In particular, we demonstrate how duality theory may be used to establish the inter-relationships between the Marshallian (or ...
Keith R. McLaren, K. K. Gary Wong
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

open access: yesFEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia   +3 more
wiley   +1 more source

The ade4 Package: Implementing the Duality Diagram for Ecologists

open access: yes
Multivariate analyses are well known and widely used to identify and understand structures of ecological communities. The ade4 package for the R statistical environment proposes a great number of multivariate methods.
Stéphane Dray, Anne-Béatrice Dufour
core  

Duality and anti-duality for allocation rules in economic problems 1: an axiomatic analysis [PDF]

open access: yes, 2018
technical ...
大石, 尊之   +3 more
core  

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