Results 81 to 90 of about 1,244,854 (330)

The Effect of the Board Characteristics and Management Entrenchment on Firm Diversification Strategy [PDF]

open access: yesراهبرد مدیریت مالی, 2017
The purpose of this paper is to examine the effect of the board characteristics and the management entrenchment on the diversification strategy at firms listed in Tehran Stock Exchange. In this regard, 110 companies were selected for the period 2008-2014.
Vahid Taghizadeh Khanqah, Mehdi Zeinali
doaj   +1 more source

Field Redefinitions, T-duality and Solutions in Closed String Field Theories

open access: yes, 2006
We investigate classical solutions in closed bosonic string field theory and heterotic string field theory that are obtained order by order starting from solutions of the linearized equations of motion, and we discuss the ``field redefinitions'' which ...
C. Bachas   +9 more
core   +4 more sources

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

No U(1) ‘electric-magnetic’ duality in Einstein gravity

open access: yesJournal of High Energy Physics
We revisit the question of whether classical general relativity obeys, beyond the linearised order, an analogue of the global U(1) electric-magnetic duality of Maxwell theory, with the Riemann tensor playing the role analogous to the field strength ...
Ricardo Monteiro
doaj   +1 more source

Heterotic-Type II duality in the hypermultiplet sector

open access: yes, 2012
We revisit the duality between heterotic string theory compactified on K3 x T^2 and type IIA compactified on a Calabi-Yau threefold X in the hypermultiplet sector.
A Ceresole   +59 more
core   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Seiberg-Witten map for D-branes in large R-R field background

open access: yesJournal of High Energy Physics, 2021
We obtain a Seiberg-Witten map for the gauge sector of multiple Dp-branes in a large R-R (p − 1)-form field background up to the first-order in the inverse R-R field background.
Chen-Te Ma
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

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