Results 31 to 40 of about 12,152 (266)

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

On the classification of duality defects in c = 2 compact boson CFTs with a discrete group orbifold

open access: yesJournal of High Energy Physics
We propose a novel approach to exploring duality defects in the c = 2 compact boson conformal field theory (CFT). This study is motivated by the desire to classify categorical symmetries, particularly duality defects, in CFTs.
Yuma Furuta
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Poisson-Lie T-duality in Double Field Theory

open access: yesPhysics Letters B, 2020
We present a formulation of Double Field Theory with a Drinfeld double as extended spacetime. It makes Poisson-Lie T-duality (including abelian and non-abelian T-duality as special cases) manifest.
Falk Hassler
doaj   +1 more source

A GENERAL DUALITY THEORY FOR CLONES

open access: yesInternational Journal of Algebra and Computation, 2013
Inspired by work of Mašulović, we outline a general duality theory for clones that will allow us to dualize any given clone, together with its relational counterpart and the relationship between them. Afterwards, we put the approach to work and illustrate it by producing some specific results for concrete examples as well as some general results that ...
openaire   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Non-invertible T-duality at any radius via non-compact SymTFT

open access: yesSciPost Physics
We extend the construction of the T-duality symmetry for the 2d compact boson to arbitrary values of the radius by including topological manipulations such as gauging continuous symmetries with flat connections.
Riccardo Argurio, Andrés Collinucci, Giovanni Galati, Ondrej Hulik, Elise Paznokas
doaj   +1 more source

New T-duality for Chern-Simons theory

open access: yesJournal of High Energy Physics, 2019
It has recently pointed out that a four-dimensional analog of Chern-Simons theory provides an elegant framework for understanding integrable models with spectral parameters.
Masahito Yamazaki
doaj   +1 more source

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