Results 101 to 110 of about 1,615,322 (259)
Internal functionals and bundle duals
If π:E→X is a bundle of Banach spaces, X compact Hausdorff, a fibered space π*:E*→X can be constructed whose stalks are the duals of the stalks of the given bundle and whose sections can be identified with the functionals studied by Seda in [1] and [2]
Joseph W. Kitchen, David A. Robbins
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
On the characterization of rectangular duals [PDF]
A rectangular partition is a partition of a rectangle into a finite number of rectangles. A rectangular partition is generic if no four of its rectangles meet at the same point.
Vinod Kumar, Krishnendra Shekhawat
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Nuclear Space Facts, Strange and Plain
We present a scenic but practical guide through nuclear spaces and their dual spaces, examining useful, unexpected, and often unfamiliar results both for nuclear spaces and their strong and weak duals.
Jeremy Becnel, Ambar Sengupta
doaj +1 more source
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
New AdS3 × S2 T-duals with N=04$$ \mathcal{N}=\left(0,4\right) $$ supersymmetry
A bstractIt is well known that Hopf-fibre T-duality and uplift takes the D1-D5 near-horizon into a class of AdS3 × S2 geometries in 11D where the internal space is a Calabi-Yau three-fold.
Y. Lozano +3 more
semanticscholar +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
DNA ligase LigE increases bacterial transformation with damaged extracellular DNA
The DNA ligase LigE from the naturally competent Gram‐negative bacterium Neisseria gonorrhoaea increases transformation with cut extracellular DNA. This process is ATP‐dependent and relies on the catalytic activity of LigE; it also requires that LigE contains an intact periplasmic localisation sequence, indicating that ligE functions in the periplasm ...
Jolyn Pan +4 more
wiley +1 more source

