Results 31 to 40 of about 11,793 (291)
Triggered Ferroelectricity in HfO2 From Hybrid Phonons and Higher‐Order Dynamical Charges
Advanced Materials, EarlyView.We combine first‐principles calculations, LGD theory and group theory to demonstrate the mechanism of hybrid‐triggered ferroelectricity in HfO2${\rm HfO}_2$, enabled by trilinear and quadlinear couplings between stable polar and nonpolar modes. HfO2${\rm HfO}_2$ hosts unconventional interplay between structure modes where substantial contribution to ...
Seongjoo Jung, Turan Birol
wiley +1 more source
Deubiquitinases as a Signaling Target of Oxidative Stress
Cell Reports, 2012 Deubiquitinating enzymes (DUBs) constitute a large family of cysteine proteases that have a broad impact on numerous biological and pathological processes, including the regulation of genomic stability.
Xiomaris M. Cotto-Rios +4 more
doaj +1 more source
The emerging role of Deubiquitinases (DUBs) in parasites: A foresight review
Frontiers in Cellular and Infection Microbiology, 2022 Before the discovery of the proteasome complex, the lysosomes with acidic proteases and caspases in apoptotic pathways were thought to be the only pathways for the degradation of damaged, unfolded, and aged proteins. However, the discovery of 26S and 20S
Prakash Kumar +4 more
doaj +1 more source
The SAGA Deubiquitinilation (DUB) Module Participates in Pol III-Dependent Transcription [PDF]
, 2021 J. V. Nikolenko +5 more
openalex +1 more source
NIR‐Activated Ag2S Quantum Dots for Efficient Broad‐Spectrum Antibacterial and Biofilm Disruption
Advanced Materials Interfaces, EarlyView.This study presents a novel non‐antibiotic strategy leveraging NIR‐activated Ag2S QDs for synergistic PTT/PDT. The platform degrades the protective extracellular matrix via localized hyperthermia, facilitating deep penetration and ROS‐induced oxidative damage.
Rui Yao +10 more
wiley +1 more source
DUBs, new members in the hypoxia signaling clUb
Frontiers in Oncology, 2016 Cellular protein homeostasis is tightly regulated by ubiquitination. Responsible for target protein ubiquitination is a class of enzymes, the so-called ubiquitin (Ub) E3-ligases.
Amelie S Schober +2 more
doaj +1 more source
Systematic analysis of the physiological importance of deubiquitinating enzymes. [PDF]
PLoS ONE, 2012 Deubiquitinating enzymes (DUBs) are proteases that control the post-translational modification of proteins by ubiquitin and in turn regulate diverse cellular pathways.
Wei-Ling Tsou +6 more
doaj +1 more source
Advanced Science, EarlyView.This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li +11 more
wiley +1 more source
The Role of Deubiquitinating Enzymes in Synaptic Function and Nervous System Diseases
Neural Plasticity, 2012 Posttranslational modification of proteins by ubiquitin has emerged as a critical regulator of synapse development and function. Ubiquitination is a reversible modification mediated by the concerted action of a large number of specific ubiquitin ligases ...
Jennifer R. Kowalski, Peter Juo
doaj +1 more source
Instructive or Constructive Teaching Approaches in the Economic Education?
Journal of Social Science Education, 2004 Even if the polarizing discussion about instructive and constructive teaching approaches is widely overcome, some misapprehensions still seem to distort the discourse.
Rolf Dubs
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