Results 111 to 120 of about 51,867 (216)

The value of dog for knowledge of human Duchenne muscular dystrophy: New findings in pathogenesis and therapeutic advances

, 2015
Duchenne muscular dystrophy (DMD) is the most devastating form of inherited muscular dystrophy in men. The loss of dystrophin causes progressive weakness and degeneration of skeletal and cardiac muscle leading to the replacement of muscle by connective ...
Malvestio, Lygia M. [UNESP], de Moraes, Flávio Ruas [UNESP], de Moraes, Julieta R. Engrácia [UNESP], Martins, Isabela M. [UNESP]   +3 more
core   +1 more source

Benefits of the Duchenne Smile and Positive Emotions. A Systematic Review

Educaţia 21
The Duchenne smile is the genuine smile characterized by the activation of the muscles around the eyes and mouth. It has been associated, in the specialized literature, with the experience of positive emotions.
Violeta Lupu-Merca, Sebastian Vaida
doaj   +1 more source

Construct Validity and Reliability of the OMNI Scale in Children and Adolescents With Neuromuscular Diseases

Muscle &Nerve, Volume 74, Issue 5, Page 1421-1428, November 2026.
ABSTRACT Introduction/Aims Children and adolescents with neuromuscular diseases often demonstrate muscle weakness and mobility limitations, which may increase perceived exertion during functional tasks. The OMNI scale was developed to assess perceived exertion in pediatric populations; however, its measurement properties in neuromuscular conditions ...
Juliana Cardoso, Clara Corsete Tonoli, Beatriz Parra Buzzetti, Gabriela Barroso Davoli, Ana Claudia Mattiello‐Sverzut   +4 more
wiley   +1 more source

Duchenne de Boulogne (1806–1875)

, 2013
Chapter 5 discusses Guillaume Benjamin Amand Duchenne, or Duchenne de Boulogne, who played a singularly important role in the history of muscular dystrophy.
Marcia L. H. Emery, Alan E. H. Emery
core   +1 more source

Modelling pollinator trends using multi‐scale environmental data from the UK Pollinator Monitoring Scheme

Ecological Solutions and Evidence, Volume 7, Issue 4, October–December 2026.
The UK Pollinator Monitoring Scheme (PoMS) generates annual data on insect pollinators from a combination of structured surveys carried out primarily by citizen scientists, covering a wide range of habitats. Our study uses 6 years of PoMS data to produce new metrics of change in abundance and species richness of bees, hoverflies and other pollinator ...
Claire Carvell, Nick J. B. Isaac, Martin C. Harvey, Robin Hutchinson, Nadine Mitschunas, Christopher Andrews, Angus Garbutt, Lucy E. Ridding, Helen E. Roy, Richard F. Comont, Richard Fox, Dawn E. Balmer, Rachel Richards, Rowan Edwards, Alfried P. Vogler, William E. Kunin, Michael P. D. Garratt, Simon G. Potts, Paul Woodcock, Francesca Mancini   +19 more
wiley   +1 more source

Two Years of Ocrelizumab Treatment in Black and Hispanic People with Multiple Sclerosis in CHIMES: A Single‐Arm Clinical Trial

Annals of Neurology, Volume 100, Issue 4, Page 793-807, October 2026.
Objective To evaluate the effectiveness and safety of ocrelizumab in self‐identified black and Hispanic people with relapsing multiple sclerosis. Methods The Characterization of Ocrelizumab in Minorities with Multiple Sclerosis (CHIMES) trial, a prospective, open‐label, single‐arm, phase 4 study, intentionally recruited underrepresented populations in ...
Lilyana Amezcua, Anthony T. Reder, Evanthia Bernitsas, Nancy L. Monson, Timothy Vartanian, Gregory F. Wu, Mansoor Saleh, Annette Okai, Ahmed Z. Obeidat, Dilraj Sokhi, Rikisha Parekh, Jinglan Pei, Christopher Harp, David Clayton, Ibraheem Abioye, Mitzi J. Williams, for the CHIMES Study Group   +16 more
wiley   +1 more source

Case Report: Home initiation of nocturnal non-invasive ventilation in two adolescents with Duchenne muscular dystrophy and comorbid autism spectrum disorder and ADHD

Frontiers in Pediatrics
This case report describes initiation of Nocturnal Non-Invasive Ventilation in home settings for two adolescents with Duchenne Muscular Dystrophy and different neuropsychiatric and neurocognitive comorbidities: one has Autism Spectrum Disorder, and the ...
Pien M. M. Weerkamp, Mark Voermans, Moniek Finders, Arno Brouwers, Philippe Collin, Philippe Collin, Sylvia Klinkenberg, Sylvia Klinkenberg, Sylvia Klinkenberg, Jos. G. M. Hendriksen, Jos. G. M. Hendriksen, Jos. G. M. Hendriksen   +11 more
doaj   +1 more source

Navigating the Prescription Drug Information System

Clinical Pharmacology &Therapeutics, Volume 120, Issue 4, Page 855-870, October 2026.
Information on new prescription drugs is increasingly complex and fragmented, posing challenges for healthcare professionals, patients, and payers. Clinicians require concise, actionable guidance to support prescribing decisions, while patients seek to balance benefits and harms when making decisions aligned with their treatment goals.
Irina V. Wang, Courtney Davis, Robin Forrest, Avi Cherla, Maximilian Siebert, Janice Cowden, Sophia Walker, Tamar Krishnamurti, Florence T. Bourgeois, Steven Woloshin, Anita K. Wagner, Huseyin Naci   +11 more
wiley   +1 more source

Rev‐erb‐α in Skeletal Muscle Adaptation: Integrating Circadian Control Mechanisms and Exercise Dynamic Responses

Journal of Cellular Physiology, Volume 241, Issue 10, October 2026.
ABSTRACT Circadian rhythms orchestrate a host of biological processes in a time‐dependent manner to maintain homeostasis in response to exercise. Within this framework, Rev‐erb‐α, an intracellular nuclear receptor and transcriptional regulator, transcends its role in circadian rhythms to drive myogenesis, muscle remodeling, primary metabolism, and ...
Ivo Vieira de Sousa Neto, Alisson Luiz da Rocha, Ana Paula Pinto, Eliézer Lucas Pires Ramos, Eduardo Rochete Ropelle, José Rodrigo Pauli, Ellen Cristini de Freitas, Adelino Sanchez Ramos da Silva   +7 more
wiley   +1 more source

MicroRNA–mRNA Networks in Skeletal Muscle of Tailored Pig Models for Dystrophinopathies

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Duchenne muscular dystrophy (DMD) and Becker muscular dystrophy (BMD) are X‐linked dystrophinopathies caused by mutations in the dystrophin (DMD) gene. A common DMD‐causing mutation in humans is exon 52 deletion (DMDΔ52), which disrupts the reading frame and abolishes dystrophin expression.
Sarah Reschke, Alexander Graf, Frieder Hadlich, Florian Jaudas, Thomas Fröhlich, Michael Stirm, Nikolai Klymiuk, Stefan Krebs, Eckhard Wolf, Asghar Ali   +9 more
wiley   +1 more source