Results 101 to 110 of about 30,575 (221)

Early and Divergent Lipid Mediator Remodelling in Fast Versus Slow Skeletal Muscles of Female hSOD1G93A Mice

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.
ABSTRACT Background Skeletal muscle atrophy in amyotrophic lateral sclerosis (ALS) drives loss of muscle strength, function and quality of life in ALS patients. The endocannabinoid system (ECS) regulates muscle homeostasis via regenerative and metabolic processes, and although ECS alterations have been reported in ALS neural tissues, ECS remodelling ...
Sebastiaan Dalle, Kaat Vanderbeke, Thibaut Burg, Moniek Schouten, Wout Lauriks, Nicole Hersmus, Ludo Van Den Bosch, Katrien Koppo   +7 more
wiley   +1 more source

Elevation of transaminases. What if not the liver?

Лечащий Врач
Background. According to Russian studies, the average age of Duchenne muscular dystrophy diagnosis is 7-8 years. This is because, on one hand, Duchenne muscular dystrophy is a rare disease, and a doctor may never see it throughout their clinical practice.
I. V. Sharkova
doaj   +1 more source

Five‐Year Outcomes With Delandistrogene Moxeparvovec in Patients With Duchenne Muscular Dystrophy: A Phase 1/2a Study

Muscle &Nerve, Volume 74, Issue 2, Page 397-403, August 2026.
ABSTRACT Aims We report 5‐year results from a phase 1/2a study of delandistrogene moxeparvovec, a recombinant adeno‐associated virus serotype rh74 vector‐based gene therapy for Duchenne muscular dystrophy (DMD), with post hoc analyses contextualizing functional outcomes. Methods Four ambulatory patients with DMD (≥ 4–< 8 years at enrollment) entered an
Jerry R. Mendell, Zarife Sahenk, Linda P. Lowes, Megan A. Iammarino, Lindsay N. Alfano, Craig M. McDonald, James E. Signorovitch, Jim Jin, Jing Li, Stefanie Mason, Louise R. Rodino‐Klapac   +10 more
wiley   +1 more source

Case Report: Home initiation of nocturnal non-invasive ventilation in two adolescents with Duchenne muscular dystrophy and comorbid autism spectrum disorder and ADHD

Frontiers in Pediatrics
This case report describes initiation of Nocturnal Non-Invasive Ventilation in home settings for two adolescents with Duchenne Muscular Dystrophy and different neuropsychiatric and neurocognitive comorbidities: one has Autism Spectrum Disorder, and the ...
Pien M. M. Weerkamp, Mark Voermans, Moniek Finders, Arno Brouwers, Philippe Collin, Philippe Collin, Sylvia Klinkenberg, Sylvia Klinkenberg, Sylvia Klinkenberg, Jos. G. M. Hendriksen, Jos. G. M. Hendriksen, Jos. G. M. Hendriksen   +11 more
doaj   +1 more source

Optimizing Care for Growth and Puberty in Duchenne Muscular Dystrophy: A Survey of Clinical Practice in the OPTIMIZE DMD Consortium

Muscle &Nerve, Volume 74, Issue 2, Page 433-439, August 2026.
ABSTRACT Introduction/Aim Optimizing Management of Endocrine Complications in Duchenne Muscular Dystrophy (OPTIMIZE DMD) is an international consortium of clinicians created to advance endocrine and bone clinical care in DMD. The aim of this study was to better understand current views and practices regarding investigation and management of growth and ...
Claire L. Wood, Funmbi Babalola, Robert W. Benjamin, Carol Lam, Laura McAdam, Stefan Nicolau, Anne Marie Sbrocchi, Mena Scavina, Julia C. Sorbara, Alexandra Ahmet, Susan Apkon, Sonum Bharill, Melissa Fiscaletti, Kathi Kinnett, Hugh J. McMillan, Nadia Merchant, Nat Nasomyont, Maria Fernanda Ochoa Molina, Nora E. Renthal, Pamela Smith, Prasanth N. Surampudi, Jaclyn G. Tamaroff, Cuixia Tian, Leanne M. Ward, David R. Weber, Sze Choong (Jarod) Wong, Janet L. Crane, Meilan M. Rutter, on behalf of the OPTIMIZE DMD Consortium, Leanne M. Ward, Pat Furlong, David R. Weber, Sze Choong (Jarod) Wong, Hugh J. McMillan, Meilan M. Rutter, Susan Apkon, Roozbeh Pourziaei Manesh, Mei Wang, Anne Marie Sbrocchi, David R. Weber, Alexandra Ahmet, Aravindhan Veerapandiyan, Medical Sciences, Hugh J. McMillan, Sze Choong (Jarod) Wong, Kathryn A. Selby, Maria‐Elena Lautatzis, Rachel Schrader, Kathi Kinnett, Meilan M. Rutter, Claire L. Wood, Anne Marie Sbrocchi, Carol Lam, Funmbi Babalola, Janet L. Crane, Julia C. Sorbara, Laura McAdam, Robert Benjamin, Stefan Nicolau, Mena Scavina, Leanne M. Ward, Sze Choong (Jarod) Wong, Kim Phung, Nat Nasomyont, Anne Marie Sbrocchi, Cuixia Tian, David R. Weber, Janet L. Crane, Maria Fernanda Ochoa Molina, Meilan M. Rutter, Melissa Fiscaletti, Nadia Merchant, Paula R. Clemens, Rana Halloun, Shipra Bansal, Stefan Nicolau, Pat Furlong, Susan Apkon, Nora E. Renthal, Amanda M. Appel, Aravind Veerapandiyan, Medical Sciences, Claire L. Wood, Gabriela Vargas, Lindsey E. Bratland, Nat Nasomyont, Natalie Truba, Prasanth N. Surampudi, Janet Hoskin, Colin Werth, Patrick Moeschen, Nadia Merchant, Jaclyn Tamaroff, Christopher Lewis, Cuixia Tian, Diana X. Bharucha‐Goebel, Philip Zeitler, Laura McAdam, Maria‐Elena Lautatzis, Meilan M. Rutter, Ryan Farrell, Rainbow Babies, Rana Halloun, Sonum Bharill, Sze Choong (Jarod) Wong, Pat Furlong, Luca Bello, Chiara Panicucci, Clelia Cipolla, Danilo Fintini, Natascia Di Iorgi, Child Health, Sabrina Corbetta, Francesca Cumbo, Alberto Ferlin, Francesco Francini, Luisa De Sanctis, Tommaso Aversa, Gianluca Tornese, Burlo Garofolo, Eugenio Maria Mercuri, Elena Mularoni, Maria Grazia D'Angelo, Bosisio Parini, Chiara Arpaia, Silvia Carrara, Pieve Emanuele, Ilaria Zito, Fernanda de Angelis, Fabiana Boccia, Gaia Relucenti, Filippo Buccella   +131 more
wiley   +1 more source

Quantitative MRI Assessment of Myotoxin‐Induced Skeletal Muscle Damage of mdx Mice

Muscle &Nerve, Volume 74, Issue 2, Page 485-491, August 2026.
ABSTRACT Introduction/Aims Although magnetic resonance imaging (MRI) has been extensively applied in dystrophic muscle, longitudinal characterization of multiple quantitative MRI parameters during degeneration and regeneration remains limited. This study aimed to longitudinally characterize changes in quantitative MRI parameters in control and ...
Ravneet Vohra, Joshua Park, Feng Zhang, Jeffrey S. Chamberlain, Donghoon Lee   +4 more
wiley   +1 more source

Proposing a Coverage With Evidence Development Framework for Accelerated Approval at the U.S. Food and Drug Administration

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 9, September 2026.
Dhanush Bearelly, Purav Desai, David T. Zhu, Rajesh Balkrishnan   +3 more
wiley   +1 more source

Quantitative Guanidinium CEST‐Based pH Mapping at 3 T in Healthy and Pathological Muscle

NMR in Biomedicine, Volume 39, Issue 8, August 2026.
Chemical exchange saturation transfer (CEST) enables high‐resolution pH mapping by measuring the exchange rate between guanidinium and water protons. The current method is based on the Z‐spectra fitting with Bloch–McConnell (BM) equations and allows us to detect pH variations on the order of 0.02 pH units in the very restrained pathophysiological pH ...
Valentin Henriet, Pierre‐Yves Baudin, Benjamin Marty, Marc Lapert, Harmen Reyngoudt   +4 more
wiley   +1 more source

Non-operative treatment for perforated gastro-duodenal peptic ulcer in Duchenne Muscular Dystrophy: a case report

BMC Surgery, 2004
Background Clinical characteristics and complications of Duchenne muscular dystrophy caused by skeletal and cardiac muscle degeneration are well known. Gastro-intestinal involvement has also been recognised in these patients.
Wever Jan, Van Royen Barend J, Oddens Jorg R, Brinkman Justus-Martijn, Olsman Jan G   +4 more
doaj  

Improving Nocturnal Non‐Invasive Positive Pressure Support Adherence in Children and Young Adults With Duchenne Muscular Dystrophy

Pediatric Pulmonology, Volume 61, Issue 8, August 2026.
ABSTRACT Background Patients with Duchenne muscular dystrophy (DMD) have progressive muscular weakness, respiratory decline and often have poor adherence to nocturnal non‐invasive positive airway pressure ventilation (NIPPV). Methods In 2020, we sought to increase nocturnal NIPPV adherence (≥ 4 h use overnight on at least 65% of nights) from 33% to 75%
John E. Pascoe, Neepa Gurbani, Daniel Ignatiuk, Carolyn Grad, Danielle M. Simmons, Mark Sketch, Olivia Rolsen, Lisa Mullen, Christine L. Schuler, Hemant Sawnani   +9 more
wiley   +1 more source