Results 81 to 90 of about 51,867 (216)

Myocardiale arbeid: plaats in de dagelijkse praktijk en toekomstperspectieven

Myocardiale arbeid, een techniek om de functie van het linkerventrikel te meten met inachtneming van drukbelasting, ontstond in de jaren '60 en '70 met de introductie van pressure volume loops.
DUCHENNE, Jürgen
core   +1 more source

Beyond conventional anthropometry: Muscle‐related indicators and muscle strength in adults with congenital heart disease: A retrospective study with a comparison group

Nutrition in Clinical Practice, EarlyView.
Abstract Anthropometric characteristics and muscle strength remain insufficiently characterized in adults with congenital heart disease (CHD). The aim of the study was to characterize anthropometric indicators and muscle strength in hospitalized adults with CHD and examine differences according to cardiac lesion complexity. Exploratory comparisons with
Hyan Ribeiro Prudêncio de Sousa, Cláudia Porto Sabino Pinho   +1 more
wiley   +1 more source

Creatine/Creatinine Ratio and Myostatin as Biomarkers to Monitor Muscle Function in Duchenne Muscular Dystrophy Patients

Journal of Cachexia, Sarcopenia and Muscle
Background Duchenne Muscular Dystrophy (DMD) is characterized by progressive muscle wasting leading to early loss of motor function. Functional tests monitor disease progression and serve as clinical trial endpoints but are influenced by maturation in ...
Chiara Degan, Roula Tsonaka, Sharon I. deVries, Nadine A. Ikelaar, Menno van derHolst, Hermien E. Kan, Erik H. Niks, Pietro Spitali   +7 more
doaj   +1 more source

Exosome-Mediated Benefits of Cell Therapy in Mouse and Human Models of Duchenne Muscular Dystrophy

Stem Cell Reports, 2018
Summary: Genetic deficiency of dystrophin leads to disability and premature death in Duchenne muscular dystrophy (DMD), affecting the heart as well as skeletal muscle.
Mark A. Aminzadeh, Russell G. Rogers, Mario Fournier, Rachel E. Tobin, Xuan Guan, Martin K. Childers, Allen M. Andres, David J. Taylor, Ahmed Ibrahim, Xiangming Ding, Angelo Torrente, Joshua M. Goldhaber, Michael Lewis, Roberta A. Gottlieb, Ronald A. Victor, Eduardo Marbán   +15 more
doaj   +1 more source

Prime editing in neuropsychiatric disorders: From mutation‐specific target selection to clinical translation

Neuroprotection, EarlyView.
Abstract Prime editing, a novel clustered regularly interspaced short palindromic repeats (CRISPR)‐based technology, fuses a reverse transcriptase (RT) to an engineered CRISPR‐associated protein 9 (Cas9) and uses a prime editing guide RNA (pegRNA)‐encoded template.
Tianshan Ji, Yuan Zhang, Jinyi Zhao, Yiping Lu, Chengkun Wang   +4 more
wiley   +1 more source

Parallelization Performances of PMSS Flow and Dispersion Modeling System over a Huge Urban Area

Atmosphere, 2019
The use of modeling as a support tool for crisis management and decision planning requires fast simulations in complex built-up areas. The Parallel Micro SWIFT SPRAY (PMSS) modeling system offers a tradeoff between accuracy and fast calculations, while ...
Oliver Oldrini, Patrick Armand, Christophe Duchenne, Sylvie Perdriel   +3 more
doaj   +1 more source

An investigation into the effects of dystrophin on the lateral mobility of muscle membrane components. [PDF]

, 1999
Dystrophin is the product of the Duchenne Muscular Dystrophy gene locus, whose absence results in progressive skeletal muscle breakdown. Despite considerable work on the localisation of dystrophin and its associated complex, its role in muscle function ...
Dutton, A.L., Dutton, Anna Louise
core  

Duchenne Muscular Dystrophy and Brain Function [PDF]

, 2012
Muscular dystrophies have historically been characterised according to clinical criteria, however in the genomic age the muscular dystrophies are now subdivided into groups according to the primary gene defect.
Morley, JW, S.I. Head, J.W. Morley, Head, S ; https://orcid.org/, Anderson, JL, J.L. Anderson   +5 more
core   +1 more source

Dynamic Interactions Among Climate, Land, Energy, and Water Systems: Insights From a Panel Vector Autoregression Approach

Sustainable Development, EarlyView.
ABSTRACT This study examines the dynamic interactions among climate conditions, land use, energy consumption, water resources, population dynamics, and economic growth within the Climate–Land–Energy–Water (CLEW) nexus across 137 countries from 2000 to 2023.
Kingsley Imandojemu, Romanus Osabohien, Damilola Felix Eluyela, Onur Yağiş, Felix Orole   +4 more
wiley   +1 more source

ANTISENSE MEDIATED DYSTROPHIN READING FRAME RESTORATION [PDF]

, 2010
Exon skipping using antisense oligonucleotides (AONs) has successfully been used to reframe the mRNA in various DMD (Duchenne muscular dystrophy) patients carrying deletions and in the mdx mouse model.
Spitali, Pietro
core