Results 131 to 140 of about 36,350 (272)

Volitional exercise elicits physiological and molecular improvements in the severe D2.mdx mouse model of Duchenne muscular dystrophy

The Journal of Physiology, EarlyView.
Abstract figure legend This study investigated the effects of volitional exercise on muscle health in the more severe D2.mdx model of Duchenne muscular dystrophy (DMD). We showed that 8–10 weeks of a relatively high volume of voluntary wheel running (VWR) in D2.mdx animals augmented select muscle mass and normalized ex vivo muscle force compared to ...
Stephanie R. Mattina, Sean Y. Ng, Andrew I. Mikhail, Derek W. Stouth, Cora E. Jornacion, Irena A. Rebalka, Thomas J. Hawke, Vladimir Ljubicic   +7 more
wiley   +1 more source

Efficacy and safety of Viltepso® in Duchenne muscular dystrophy: review of clinical studies

Русский журнал детской неврологии
The author presents a literature review on the safety and efficacy of antisense oligonucleotides in the treatment of Duchenne muscular dystrophy using the exon skipping method using Viltepso® (viltolarsen), the only drug of this class registered in ...
V. M. Suslov, D. I. Rudenko
doaj   +1 more source

Petides in Duchenne muscular dystrophy. [PDF]

, 1977
Stanley J. Gross
openalex   +1 more source

Chromatography in Downstream Processing of Recombinant Adeno‐Associated Viruses: A Review of Current and Future Practises

Biotechnology and Bioengineering, Volume 122, Issue 5, Page 1067-1086, May 2025.
ABSTRACT Recombinant adeno‐associated virus (rAAV) has emerged as an attractive gene delivery vector platform to treat both rare and pervasive diseases. With more and more rAAV‐based therapies entering late‐stage clinical trials and commercialization, there is an increasing pressure on the rAAV manufacturing process to accelerate drug development ...
Julius Klemens Lorek, Madelène Isaksson, Bernt Nilsson   +2 more
wiley   +1 more source

Serum enzyme studies in muscle disease: Part III Serum creatine kinase activity in relatives of patients with the Duchenne type of muscular dystrophy

, 1964
John Pearce, R. J. Pennington, J. N. Walton   +2 more
openalex   +1 more source

POSSIBILITY OF PRENATAL DIAGNOSIS OF DUCHENNE MUSCULAR DYSTROPHY (DMD) [PDF]

, 1977
Florence P. Haseltine, Maurice J Mahonev, John C. Hobbins, C. Thomas Caskey, Leon Roaenberg   +4 more
openalex   +1 more source

All hands on deck: The multidisciplinary rehabilitation assessment and management of hand function in persons with neuromuscular disorders

Muscle &Nerve, Volume 71, Issue 5, Page 869-888, May 2025.
Abstract Hand function is important in every aspect of our lives. Across a wide range of neuromuscular disorders—inherited ataxias, motor neuron diseases, polyneuropathies, and myopathies—people can experience losses in hand strength, tone, movement, dexterity, joint range, and sensation.
Colleen O'Connell, Meiqi Guo, Béatrice Soucy, Marla Calder, Jeff Sparks, Stephanie Plamondon   +5 more
wiley   +1 more source

An overview of current prenatal genetic screening and diagnosis guidelines

Pregnancy, Volume 1, Issue 3, May 2025.
Abstract The landscape of prenatal genetics continues to evolve rapidly, with improvements in processing speed and technology. Clinicians are tasked with staying current with the latest recommendations for prenatal genetic screening and diagnosis in order to provide patient‐centered and evidence‐based care. We present a review of 15 societal guidelines
Carmen M. A. Santoli, Sarah K. Dotters‐Katz, Teresa N. Sparks, Jeffrey A. Kuller   +3 more
wiley   +1 more source

Predictive Modeling For Real-Time Personalized Health Monitoring in Muscular Dystrophy Management [PDF]

arXiv
Muscular Dystrophy is a group of genetic disorders that progressively affect the strength and functioning of muscles, thereby affecting millions of people worldwide. The lifetime nature of MD requires continuous follow-up care due to its progressive nature.
arxiv  

Correlation of clinical and deletion data in Duchenne and Becker muscular dystrophy. [PDF]

, 1989
Shirley Hodgson, K Hart, Stephen Abbs, J Z Heckmatt, E. Rodillo, Martin Bobrow, Victor Dubowitz   +6 more
openalex   +1 more source