Duck Tembusu virus (DTMUV) is a recently emerging pathogenic flavivirus that has resulted in a huge economic loss in the duck industry. However, no vaccine is currently available to control this pathogen.
Zhong Zou, Zhigang Liu, Meilin Jin
doaj +1 more source
Cytokines of Birds: Conserved Functions [PDF]
Targeted disruptions of the mouse genes for cytokines, cytokine receptors, or components of cytokine signaling cascades convincingly revealed the important roles of these molecules in immunologic processes. Cytokines are used at present as drugs to fight
Göbel, Thomas W. F.+4 more
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Modulation of Functional Activities of Chicken Heterophils by Recombinant Chicken IFN-γ [PDF]
The objective of the present studies was to examine the in vitro effects of recombinant chicken interferon-γ (rChIFN-γ) on shape change, phagocytosis, and the oxidative/nonoxidative killing activities of day-old chicken heterophils.
B. Kaspers+12 more
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Live Attenuated Vaccine based on Duck Enteritis Virus against Duck Hepatitis A Virus Types 1 and 3
As causative agents of duck viral hepatitis, duck hepatitis A virus type 1 (DHAV-1) and type 3 (DHAV-3) causes significant economic losses in the duck industry.
Zhong Zou+10 more
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Truncation of the NS1 protein converts a low pathogenic avian influenza virus into a strong interferon inducer in duck cells [PDF]
The NS1 protein of influenza A viruses is known as a nonessential virulence factor inhibiting type I interferon (IFN) production in mammals and in chicken cells. Whether NS1 inhibits the induction of type I IFNs in duck cells is currently unknown.
Guérin, Jean-Luc+3 more
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MVA-based H5N1 vaccine affords cross-clade protection in mice against influenza A/H5N1 viruses at low doses and after single immunization. [PDF]
Human infections with highly pathogenic avian influenza viruses of the H5N1 subtype, frequently reported since 2003, result in high morbidity and mortality.
Amerongen, Geert van+10 more
core +8 more sources
Construction and characterization of H5N1-recombinant fowlpox viruses co-expressing host cytokines [PDF]
Possessing a large double stranded DNA genome up to 300 kb, fowlpox virus (FWPV) has been developed to express avian influenza virus (AIV) antigens since the late 1980s. A more advanced approach would be to coexpress host cytokines from such recombinants.
Abdul Razak, Mariatulqabtiah+1 more
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Live attenuated vaccines are widely used to protect humans or animals from pathogen infections. We have previously developed a chicken embryo-attenuated Duck Hepatitis A Virus genotype 1 (DHAV-1) vaccine (CH60 strain).
Xumin Ou+48 more
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The extraordinary evolutionary history of the reticuloendotheliosis viruses [PDF]
The reticuloendotheliosis viruses (REVs) comprise several closely related amphotropic retroviruses isolated from birds. These viruses exhibit several highly unusual characteristics that have not so far been adequately explained, including their extremely
A Katzourakis+95 more
core +3 more sources
The evolution of IL-4 and IL-13 and their receptor subunits [PDF]
Peer ...
Secombes, Christopher J., Wang, Tiehui
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