Results 91 to 100 of about 2,610,836 (314)

Prediction of Sentinel Lymph Node Metastasis in Breast Ductal Carcinoma In Situ Diagnosed by Preoperative Core Needle Biopsy

Frontiers in Oncology, 2020
Purpose The positivity of sentinel lymph node (SLN) metastasis is relatively low in ductal carcinoma in situ (DCIS) patients. The aim of this study was to investigate factors associated with SLN metastasis and build a model to predict the potential risk ...
Kai Zhang, Lang Qian, Qian Zhu, Cai Chang   +3 more
semanticscholar   +1 more source

Ductal carcinoma in situ (DCIS) [PDF]

, 2010
Ductal carcinoma in situ (DC IS) is a breast malignancy that is characterized by the proliferation of malignant ductal epithelial cells without evidence of invasion through the basement membrane.
Vassallo, Pierre
core  

Immunohistochemical evaluation of human epidermal growth factor receptor 2 and estrogen and progesterone receptors in breast carcinoma in Jordan [PDF]

, 2005
INTRODUCTION: Although breast carcinoma (BC) is the most common malignancy affecting Jordanian females and the affected population in Jordan is younger than that in the West, no information is available on its biological characteristics. Our aims in this
AA Abalkhail, AM Ruder, B Zafrani, CR De Potter, CW Elston, D Varshney, DC Allred, DH Choi, DJ Slamon, DJ Slamon, DJ Slamon, E May, Early Breast Cancer Trialists' Collaborative Group, ER Hoff, F Revillion, G Abadjian, G Arpino, G Pauletti, G Pauletti, GN Hortobagyi, HB Muss, J Ashba, J Yang, JA Ligibel, JM Esteban, Jordan Cancer Registry, Ministry of Health, JS Huston, JS Ross, K McKeage, LC Hartmann, LJ Layfield, LK Shawver, M Ferno, M Stierer, MF Kamal, Mohammad Al Hamad, Nidal M Almasri, O Stal, PL Porter, RH Mohammed, S Chariyalertsak, S Eppenberger-Castori, S Paik, S Taucher, SI Rosenthal, SS Amr, T el-A Helal, T Rajkumar, U Berger, W Hanna, WF Anderson, YF Dajani   +51 more
core   +2 more sources

Exploring the Latent Information in Spatial Transcriptomics Data via Multi‐View Graph Convolutional Network Based on Implicit Contrastive Learning

Advanced Science, EarlyView.
STMIGCL is an implicit contrastive learning‐based multi‐view graph convolutional network framework designed for downstream tasks such as spatial domain recognition, trajectory inference, and spatially variable gene identification. By combining multi‐view learning with contrastive learning and employing contrastive learning methods that enhance contrast
Sheng Ren, Xingyu Liao, Farong Liu, Jie Li, Xin Gao, Bin Yu   +5 more
wiley   +1 more source

Thymoquinone induces apoptosis in temozolomide‐resistant glioblastoma cells via the p38 mitogen‐activated protein kinase signaling pathway

Environmental Toxicology, Volume 38, Issue 1, Page 90-100, January 2023., 2023
Abstract Temozolomide (TMZ) can cross the blood‐brain barrier (BBB) and deliver methyl groups to the purine (guanine) bases of DNA, leading to mispairing during DNA replication and subsequent cell death. However, increased expression of the repair enzyme methyl guanine methyltransferase (MGMT), which removes methyl groups from purine bases, counteracts
Ai Mai, Shu‐Wen Ye, Jia‐Yu Tu, Jun Gao, Zhan‐Fang Kang, Qian‐Ming Yao, Wei‐Jen Ting   +6 more
wiley   +1 more source

An atypical presentation of infiltrating ductal carcinoma

Journal of Family Medicine and Primary Care, 2016
A 64-year-old African-American female presented with nonbloody nipple discharge. Clinical and cytological examination of the discharge was normal. The mammography suggested pleomorphic calcification in the left breast. A stereotactic biopsy showed ductal
Kunal Kishor Jha, Suresh Kumar Gupta
doaj   +1 more source

Occurrence of Residual Cancer Within Re-excisions After Subcutaneous Mastectomy of Invasive Breast Cancer and Ductal Carcinoma In Situ – A Retrospective Analysis

In Vivo, 2020
Background/Aim: Surgical margin status remains an important determinant for recurrence of invasive breast cancer and ductal carcinoma in situ. We compared the number of positive margins in initial histology with rates of residual tumor in re-excision ...
C. Pahmeyer, A. Schablack, D. Ratiu, F. Thangarajah, S. Ludwig, Berthold Gruettner, P. Mallmann, W. Malter, M. Warm, C. Eichler   +9 more
semanticscholar   +1 more source

Spectral morphometric characterization of breast carcinoma cells [PDF]

The spectral morphometric characteristics of standard haematoxylin and eosin breast carcinoma specimens were evaluated by light microscopy combined with a spectral imaging system. Light intensity at each wavelength in the range of 450–800 nm was recorded
AE Dawson, B Stenkvist, BA Stoll, C Rothmann, C Rothmann, CJ Cornelisse, D DiConstanzo, D Spina, DD Komitowski, DD Komitowski, DL Page, E Schrock, ER Farmer, ER Fisher, GH Heppner, GH Yu, HS Gallager, HSG Gundersen, I Barshack, IO Ellis, J Kopolovic, JG Azzopardi, JPA Baak, KJ Pienta, KW Gilchrist, M Eskelinen, M Ladekarl, M Ladekarl, MD Lagios, R Smith, RS du Toit, RW Scarff, S Toikkanen, T Veldman, W Galbraith, WA Wells, WH Hartmann, WJ Lennington, Y Garini, Y Garini, Z Malik, Z Malik, Z Malik, Z Malik   +43 more
core   +2 more sources

Declining recurrence among ductal carcinoma in situ patients treated with breast-conserving surgery in the community setting [PDF]

, 2011
Introduction: Randomized trials indicate that adjuvant radiotherapy plus tamoxifen decrease the five-year risk of recurrence among ductal carcinoma in situ patients treated with breast-conserving surgery from about 20% to 8%.
American Cancer Society, Ann M Geiger, B Fisher, B Fisher, B Fisher, B Fisher, B Fisher, B Fisher, B Fisher, Balaram Puligandla, C Dunne, Charles P Quesenberry, CI Li, CI Li, DL Wickerham, ER Fisher, ER Fisher, GF Schwartz, J Houghton, J Kalbfleisch, JP Julien, K Kerlikowske, K Rothman, LA Habel, Larissa Nekhlyudov, Laura C Collins, Laurel A Habel, Luana Acton, MD Lagios, MD Lagios, MJ Silverstein, MJ Silverstein, MS Pepe, N Bijker, N Bijker, N Bijker, Ninah S Achacoso, NN Baxter, Reina Haque, RL Prentice, RW Carlson, S Hetelekidis, SA Joslyn, SJ Schnitt, SO Emdin, Stuart J Schnitt, Suzanne W Fletcher, TW Yen, VL Ernster, VL Ernster   +49 more
core   +2 more sources

Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy

Advanced Science, EarlyView.
Meisoindigo targets PKMYT1 for degradation by acting as a molecular glue that enhances PKMYT1‐TRIM25 interaction, leading to K48‐linked ubiquitination and subsequent proteasomal degradation, thereby exerting therapeutic effects in chronic myeloid leukemia.
Zhao‐Xin Zhang, Shu‐Ying Li, Fang‐Fei Li, Qin‐Yan Shi, Cheng‐Yong Tan, Xiao‐Jing Wang, Mi Li, Yun‐Bao Liu, Jing Jin, Yong Li, Shi‐Shan Yu   +10 more
wiley   +1 more source