Results 91 to 100 of about 103,945 (310)

Overdiagnosis and overtreatment of breast cancer: Overdiagnosis in randomised controlled trials of breast cancer screening [PDF]

, 2005
Data from randomised controlled trials of mammographic screening can be used to determine the extent of any overdiagnosis, as soon as either a time equivalent to the lead-time has elapsed after the final screen, or the control arm has been offered ...
AB Miller, AB Miller, AB Miller, AB Miller, FE Alexander, FE Alexander, H Vainio, I Andersson, J Frisell, L Tabar, MF Yen, N Bjurstam, S Moss, S Moss, S Shapiro, S Shapiro, Sue Moss, SW Duffy, The Breast Screening Frequency Trial Group   +18 more
core   +3 more sources

Allogeneic Immune Cell Perfusion Inhibits the Growth of Vascularized 3D In Vitro Tumor Models, Induces Vascular Regression and Desmoplasia, but Promotes Tumor Cell Invasion

Advanced Science, EarlyView.
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab, Rasika Daware, Marcelo A. Szymanski de Toledo, Oskar Weber, Dimitris Kapsokalyvas, Twan Lammers, Horst Fischer, Federica De Lorenzi, Fabian Kiessling   +8 more
wiley   +1 more source

Consultoria em patologia cirúrgica mamária: variabilidade interobservador no diagnóstico de lesões proliferativas intraductais atípicas Consultation in breast surgical pathology: interobserver diagnostic variability of atypical intraductal proliferative lesions

Revista Brasileira de Ginecologia e Obstetrícia, 2013
OBJETIVO: Avaliar a concordância nos diagnósticos histopatológicos de lesões mamárias proliferativas intraductais entre patologistas gerais e especialistas em patologia mamária.
Amanda Arantes Perez, Débora Balabram, Marcio de Almeida Salles, Helenice Gobbi   +3 more
doaj  

Multiple gene aberrations and breast cancer: lessons from super-responders. [PDF]

, 2015
BackgroundThe presence of multiple molecular aberrations in patients with breast cancer may correlate with worse outcomes.Case presentationsWe performed in-depth molecular analysis of patients with estrogen receptor-positive, HER2-negative, hormone ...
Atkins, Johnique T, Janku, Filip, Kurzrock, Razelle, Moulder, Stacy L, Stephens, Philip J, Wheler, Jennifer J, Yelensky, Roman   +6 more
core   +2 more sources

Real‐Time In Vivo Cellular‐Level Imaging During Puncture

Advanced Science, EarlyView.
We present an artificial‐intelligence‐empowered integrative‐light‐field microendoscopy (AIM) needle that delivers real‐time in vivo, diffraction‐limited cellular‐level imaging during puncture and visualizes layered microstructures along the needle path. As a microscopic complement to CT/ultrasound, it improves sampling localization and adds preliminary
Huifang Gao, Jiakang Shao, Quanzhi Li, Yizhou Tan, Liangliang Huang, Xiaorong Xu, Ji Qi, Julin Xiao, Wenwen Li, Zhong Wen, Le Wang, Xu Liu, Qing Yang, Ying Gu   +13 more
wiley   +1 more source

Cause-specific mortality after a diagnosis of ductal carcinoma in situ: Associations with screening and socio-economic status. [PDF]

Int J Cancer
What's new? Ductal carcinoma in situ (DCIS) fails to progress to invasive breast cancer (IBC) in about four‐fifths of women. Nonetheless, once advanced to IBC, risk of death increases. Here, the authors investigated breast cancer mortality in Dutch women with DCIS in light of potential associations with socioeconomic status (SES) and DCIS detection ...
Schmitz RSJM, van den Belt-Dusebout AW, van Seijen M, Verschuur EAJ, van Duijnhoven FH, Schaapveld M, Lips EH, Wesseling J, Schmidt MK.   +8 more
europepmc   +2 more sources

Disability in young people and adults one year after head injury: prospective cohort study [PDF]

, 2000
OBJECTIVE: To determine the frequency of disability in young people and adults admitted to hospital with a head injury and to estimate the annual incidence in the community.
McEwen, J., Murray, G.D., Penny, K.I., Roy, C., Teasdale, G.M., Thornhill, S.   +5 more
core   +2 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Collision of ductal adenocarcinoma and neuroendocrine tumor of the pancreas: a case report and review of the literature [PDF]

, 2017
Background: Simultaneous occurrence of exocrine and neuroendocrine tumors of the pancreas is very infrequent. We report a patient with an endocrine tumor in the pancreatic-duodenal area and extensive exocrine carcinoma involving the whole pancreas.
Blandamura, Stella, Da Dalt, Gianfranco, Merigliano, Stefano, Pozza, Gioia, Serafini, Simone, Sperti, Cosimo, Valmasoni, Michele   +6 more
core   +2 more sources

SAGE: Spatially Aware Gene Selection and Dual‐View Embedding Fusion for Domain Identification in Spatial Transcriptomics

Advanced Science, EarlyView.
SAGE is a unified framework for spatial domain identification in spatial transcriptomics that jointly models tissue architecture and gene programs. Topic‐driven gene selection (NMF plus classifier‐based scoring) highlights spatially informative genes, while dual‐view graph embedding fuses local expression and non‐local functional relations.
Yi He, Yunpei Xu, Liqing Ding, Hong‐Dong Li, Yaohang Li, Shaokai Wang   +5 more
wiley   +1 more source