Results 111 to 120 of about 53,802 (245)

In situ-like morphology in invasive ductal carcinoma: association with HER2 gene aberrations and neuroendocrine differentiation

, 2021
Invasive ductal carcinoma, NOS may exhibit a unique ductal carcinoma in-situ-like morphology characterized by lack of myoepithelial layer. Herein we described clinicopathological and im- munohistochemical features, as well as hormonal and HER2 ...
Üner, Meral, Yıldırım, Selma, Kösemehmetoğlu, Kemal   +2 more
core  

Five Decades of Innovation—Tailored Breast Cancer Treatment: 1976–2026

World Journal of Surgery, EarlyView.
Ipshita Prakash, Pooja Ramakant, Sandra Krishnan, Sharon W. W. Chan, Tadahiko Shien, Kavitha Daester, Michael Douek, Mee Hoong See, Jacqueline Jeruss, Cheng‐Har Yip, Ines Buccimazza   +10 more
wiley   +1 more source

Pathological assessment of tumour beds in breast excisions post‐neoadjuvant therapy: a retrospective cohort study

Histopathology, EarlyView.
Pathological assessment of post‐neoadjuvant treatment (NAT) breast specimens uses more laboratory resources compared with non‐NAT cases. The highest resource utilization (specimen resampling, number of tissue blocks submitted, pathologist review) occurred when the tumour bed is not grossly identifiable.
Angela Cheng, Penelope Barnes, Daniel Rayson, Christopher Liwski, Gillian Bethune   +4 more
wiley   +1 more source

Expert Consensus on the Combined Application of Radiotherapy and Novel Systemic Agents in Breast Cancer Treatment

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT The rapid advancement of radiotherapy techniques and systemic anticancer agents has created unprecedented opportunities to improve outcomes for breast cancer patients, while also introducing new challenges related to optimal integration and safety.
Jie Lan, Wenyi Zhou, Qiufan Zheng, Lu Cao, Wenyan Chen, Zhenyu He, Chunling Jiang, Yanchu Li, Wen Xia, Huihua Xiong, Xiaoli Yu, Jun Zhang, Jianli Zhao, Yanxia Zhao, Lei Liu, Xin Wu, Shusen Wang, Xiaobo Huang, Jing Jing   +18 more
wiley   +1 more source

Zebrafish as a practical and convenient model for the study of photodynamic and photothermal therapy of solid tumors: A scoping review

Photochemistry and Photobiology, EarlyView.
Zebrafish provide a high‐throughput, optically transparent platform for cancer and drug screening. Their ~80% genetic homology, xenograft compatibility, and transgenic strains enable targeted photosensitizer screening, real‐time ROS and tumor imaging, and mechanistic assays, while fish embryo acute toxicity (FET) and in vitro tests streamline toxicity ...
Ethan Wilson, Alexander Fiorentino, Brian W. Booth, Valery Bliznyuk, Diana Ivankovic, Luigi Boccuto   +5 more
wiley   +1 more source

Thymidine kinase 1 expression in atypical ductal hyperplasia significantly differs from usual ductal hyperplasia and ductal carcinoma in situ: A useful tool in tumor therapy management

, 2009
Thymidine kinase 1 (TK1) is an enzyme involved in the synthesis of DNA precursors. In studies using immunohistochemistry, it was reported to be a more useful proliferation marker than Ki-67 and PCNA in breast, lung and colorectal carcinoma. In this study,
Sveriges lantbruksuniversitet., Eriksson, Staffan,   +1 more
core   +1 more source

Transcriptomic Profiling of Canine Mammary Tumours Reveals Significant Heterogeneity Between and Within Histological Classes

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT This study presents a comprehensive transcriptomic analysis of 128 canine mammary tumours (CMTs), aiming to characterize their molecular landscape. Differential gene expression analysis (DGE), gene set enrichment analysis (GSEA) and clustering based on the human PAM50 gene panel were applied to explore molecular differences between the ...
Ingrid Marie Moberg, Nina Hansen, Helga Bergholtz, Kaja Sverdrup Borge, Gjermund Gunnes, Ellen Frøysadal Arnet, Ole Albert Guttersrud, Monica Hongrø Solbakken, Frode Lingaas   +8 more
wiley   +1 more source

Ductal carcinoma in situ

, 2018
Ductal carcinoma in situ (DCIS) is a premalignant lesion in the breast. It is often asymptomatic and diagnosed by screening mammography. DCIS is treated in line with low-risk invasive breast cancer including mastectomy or breast-conserving treatment plus
Langhans, Linnea, Skaar, Marica, Kroman, Niels, Mertz, Birgitte   +3 more
core  

Ductal carcinoma in-situ (DCIS) [PDF]

, 2013
Part 2 of this article may be found through this link: https://www.um.edu.mt/library/oar//handle/123456789/13815Ductal carcinoma in-situ (DCIS) is a noninvasive malignancy and a potential precursor to invasive cancer at pathologic analysis, DCIS shows
Vassallo, Pierre
core  

An Update on Early‐Onset Breast Cancer: Incidence, Risk Factors, Genetic Testing, and Treatment

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Early‐onset breast cancer presents in patients typically under the age of 40, while very early‐onset breast cancer is usually viewed as breast cancer occurring before the age of 35. Early‐onset breast cancer demonstrates specific molecular properties and has worse outcomes compared to its late‐onset breast cancer counterpart.
Leila Jahangiri
wiley   +1 more source