Results 121 to 130 of about 1,556 (213)

Novel and emerging skin carcinomas and adnexal tumours

Histopathology, EarlyView.
The present review aims to provide an overview of the main emerging skin epithelial tumours, with particular emphasis on salivary gland analogue sweat gland tumours and poorly differentiated carcinomas. Epidermal and adnexal tumours of the skin constitute a complex and heterogeneous group of neoplasms, with distinct morphology and behaviour.
Thibault Kervarrec, Maxime Battistella, Nicolas Macagno   +2 more
wiley   +1 more source

Clinicopathological and molecular comparison of eosinophilic solid and cystic renal cell carcinoma and TFEB‐amplified renal cell carcinoma: a comprehensive study of 15 cases

Histopathology, EarlyView.
This study supports the need for ancillary testing to diagnose ESC‐RCC versus TFEB‐amplified RCC, as neither morphology nor immunohistochemistry is sufficiently specific to distinguish these entities. The underlying molecular drivers in each tumour are pathogenic TSC1 or TSC2 gene variants in ESC‐RCC and TFEB gene amplification in TFEB‐amplified RCC ...
Hayley Zullow, Melissa Y. Tjota, Jung Woo Kwon, Tatjana Antic   +3 more
wiley   +1 more source

Far‐field bioluminescent immune cell–mediated photodynamic therapy is limited by photon flux

Photochemistry and Photobiology, EarlyView.
Bioluminescent immune cell‐mediated photodynamic therapy uses tumor‐homing, luciferase‐expressing immune cells as internal light sources to activate photosensitizers in deep‐seated and/or micrometastatic tumors. Using both experiments and computational simulations, we find that this approach delivers insufficient far‐field energy to tumor cells to ...
Ji Tae Park, Sudip Timilsina, Rebecca C. Harman, Chi‐Yong Eom, Jeonghyun Oh, Qianqian Fang, Nozomi Nishimura, Chris B. Schaffer, Bryan Q. Spring   +8 more
wiley   +1 more source

Scaling temporal resolution from mice to humans: Challenges and innovations in preclinical imaging of translational models

The Journal of Physiology, EarlyView.
Abstract figure legend Temporal scaling physiology differs significantly between mice and humans. Mice have higher metabolism, heart and respiratory rate, as well as faster blood flow rates, brain activity and physiological dynamics over time. These differences influence the temporal resolution needed in preclinical imaging of mouse models to ...
Sara Gargiulo, Matteo Gramanzini
wiley   +1 more source

Evaluation of Additional Treatment for Residual Cases After Endoscopic Papillectomy of Duodenal Ampullary Tumors

DEN Open, Volume 7, Issue 1, April 2027.
ABSTRACT Background and Aims This study aimed to assess the prognosis and outcomes of additional treatment for residual adenocarcinoma and adenoma following endoscopic papillectomy (EP) for ampullary tumors. Methods Of 191 patients who underwent EP, 43 with adenocarcinoma or adenoma and either positive or unknown pathological margins were included ...
Yusuke Kurita, Keiki Nagai, Noriki Kasuga, Kensuke Kubota, Yuji Fujita, Yusuke Sekino, Hiroki Uechi, Yuji Koyama, Shintaro Tsujikawa, Shota Matsumoto, Shigeki Tamura, Yu Honda, Shin Yagi, Takeshi Iizuka, Sho Hasegawa, Takamitsu Sato, Kunihiro Hosono, Noritoshi Kobayashi, Yuki Honma, Ryusei Matsuyama, Jotaro Harada, Masato Yoneda, Satoshi Fujii, Itaru Endo, Atsushi Nakajima   +24 more
wiley   +1 more source

An Update on Early‐Onset Breast Cancer: Incidence, Risk Factors, Genetic Testing, and Treatment

Computational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Early‐onset breast cancer presents in patients typically under the age of 40, while very early‐onset breast cancer is usually viewed as breast cancer occurring before the age of 35. Early‐onset breast cancer demonstrates specific molecular properties and has worse outcomes compared to its late‐onset breast cancer counterpart.
Leila Jahangiri
wiley   +1 more source

Breast Cancer Outcomes From Ductal Carcinoma In Situ: A Population‐Based Cohort Study

International Journal of Cancer, Volume 159, Issue 8, Page 1917-1927, 15 October 2026.
Women with ductal carcinoma in situ have an elevated risk of subsequent invasive breast cancer, but how this risk evolves over time is unclear. In this population‐based study of ethnically diverse women diagnosed between 2000 and 2022 in New Zealand, the risk of invasive ipsilateral breast cancer persisted beyond 5 years.
Qian Chen, Ian Campbell, Mark Elwood, Alana Cavadino, Phyu Sin Aye, Sandar Tin Tin   +5 more
wiley   +1 more source

Radiological Tumor Calcification in Sinonasal Adenocarcinoma: Prevalence and Prognostic Implications

Laryngoscope Investigative Otolaryngology, Volume 11, Issue 5, October 2026.
Radiological intratumoral calcifications in sinonasal adenocarcinoma have been scarcely investigated. This study aimed to assess their prevalence and evaluate their potential prognostic significance and to examine its association with surgical resectability. ABSTRACT Objective(s) Radiological intratumoral calcifications in sinonasal adenocarcinoma have
Julia Fanchette, Florian Chatelet, Melania Bertolini, B. Boukebous, Alessandro Vinciguerra, Martina Conti, Jean Pierre Guichard, Khaled Al Tabaa, Michel Wassef, Homa Adle‐Biassette, Philippe Herman, Benjamin Verillaud   +11 more
wiley   +1 more source

Clinical and Molecular Features of BAP1‐Mutated Meningiomas: Case Series

Molecular Carcinogenesis, Volume 65, Issue 10, Page 1343-1350, October 2026.
ABSTRACT BRCA1‐associated protein 1 (BAP1)‐deficient meningiomas represent a clinically and molecularly distinct subgroup with variable histology and aggressive behavior that may not be fully captured by current grading criteria. The clinical spectrum of BAP1 alterations in meningiomas, including both somatic and germline contexts, remains incompletely
Ivan Pradilla, Rasha Alfattal, Susan L. McGovern, Shaan M. Raza, Franco DeMonte, Leomar Y. Ballester, Chirag B. Patel, Carlos Kamiya‐Matsuoka   +7 more
wiley   +1 more source

Beyond the Fixed Charge: A New On‐Tissue Derivatisation Strategy Employing Photoionisable Chromophores for Mass Spectrometry Imaging of Amino‐Containing Metabolites

Angewandte Chemie, Volume 138, Issue 37, 7 September 2026.
We introduce a novel chemical derivatisation strategy for the UV‐activated detection of elusive metabolites. Incorporation of a tocopherol‐active chromophore allows for the detection of tagged analytes as photoionised radical cations, selectively induced by a 266 nm laser.
Sofia R. McGowan, Andrew J. Tague, Ashna A. Kumar, Marie Ranson, Christopher J. T. Hyland, Shane R. Ellis   +5 more
wiley   +2 more sources