Results 111 to 120 of about 2,610,836 (314)

Plasma DNMT1 Activity for Assessing Tumor Burden and Predicting Neoadjuvant Therapy Response in Breast Cancer

Advanced Science, EarlyView.
In this work, a detection method is presented for the activity of plasma DNA methyltransferase 1 (DNMT1), namely DNMT1 Identification by Variable Activity (DIVA). DIVA can detect plasma DNMT1 at levels as low as 10−7 U mL−1, also it successfully evaluated tumor burden and predicted the neoadjuvant therapy responses of breast cancer patients.
Yingran Wang, Guozhi Zhang, Zhizhao Zhang, Mengsi Zhang, Jiao Chen, Ke Wang, Lu Liu, Jing Bao, Ming Chen, Xiaowei Qi, Mingxuan Gao   +10 more
wiley   +1 more source

INVESTIGATING INVASION IN DUCTAL CARCINOMA IN SITU WITH TOPOGRAPHICAL SINGLE CELL GENOME SEQUENCING [PDF]

, 2018
Synchronous Ductal Carcinoma in situ (DCIS-IDC) is an early stage breast cancer invasion in which it is possible to delineate genomic evolution during invasion because of the presence of both in situ and invasive regions within the same sample.
Casasent, Anna, Casasent, Anna
core   +1 more source

Clinical-pathological features of an occult mixed mucinous male breast cancer. a case report [PDF]

, 2017
Mucinous carcinoma of the male breast is an uncommon malignant breast neoplasm and its diagnoses remain difficult. It is probably due to such a low rate of breast cancer cases that men tend to be diagnosed at an older age than women and with a later ...
Bonifacino, Adriana, Carico, Elisabetta, Giarnieri, Enrico, Giovagnoli, Maria Rosaria, Lamberti, Ilaria, Mancini, Rita, Scarpino, Stefania, Villani, Sandra   +7 more
core   +1 more source

Precision‐Guided Stealth Missiles in Biomedicine: Biological Carrier‐Mediated Nanomedicine Hitchhiking Strategy

Advanced Science, EarlyView.
Diagram illustrating the binding methods of NPs and biological barriers. The biological carrier‐mediated nanomedicine hitchhiking strategy (BCM‐NHS) utilizes two distinct techniques: the surface‐based “Backpack” method, which relies on ligand‐receptor binding, covalent conjugation, and non‐covalent binding, and the encapsulated “Trojan horse” approach,
Yuyan Zhou, Xinyue Wang, Deyu Zhang, Hanxiao Cui, Xiaorong Tian, Wei Du, Zhenghui Yang, Dongling Wan, Zhiwei Qiu, Chao Liu, Zhicheng Yang, Lizhihong Zhang, Qiusheng Yang, Xuefeng Xu, Wenhao Li, Dong Wang, Haojie Huang, Wencheng Wu   +17 more
wiley   +1 more source

Visualizing adverse events in clinical trials using correspondence analysis with R-package visae [PDF]

arXiv, 2021
We propose to apply stacked CA using contribution biplots as a tool to explore differences in AE data among treatments in clinical trials. We defined five levels of refinement for the analysis based on data derived from the Common Terminology Criteria for Adverse Events (CTCAE) grades, domains, terms and their combinations.
arxiv  

RTOG 9804: a prospective randomized trial for good-risk ductal carcinoma in situ comparing radiotherapy with observation.

Journal of Clinical Oncology, 2015
PURPOSE The Radiation Therapy Oncology Group 9804 study identified good-risk patients with ductal carcinoma in situ (DCIS), a breast cancer diagnosis found frequently in mammographically detected cancers, to test the benefit of radiotherapy (RT) after ...
B. McCormick, K. Winter, C. Hudis, H. Kuerer, E. Rakovitch, Barbara L. Smith, N. Sneige, J. Moughan, A. Shah, I. Germain, A. Hartford, A. Rashtian, E. Walker, A. Yuen, E. Strom, Jeannette L Wilcox, L. Vallow, W. Small, A. Pu, K. Kerlin, J. White   +20 more
semanticscholar   +1 more source

Can high-frequency ultrasound predict metastatic lymph nodes in patients with invasive breast cancer? [PDF]

, 2004
Aim To determine whether high-frequency ultrasound can predict the presence of metastatic axillary lymph nodes, with a high specificity and positive predictive value, in patients with invasive breast cancer.
Clough, G.R., Haigh, L.I.G., Truscott, J.   +2 more
core   +2 more sources

Label‐Free Microscale Technologies for Isolation of Heterogeneous Circulating Tumor Cells

Advanced NanoBiomed Research, EarlyView.
The isolation of circulating tumor cells (CTCs) from liquid biopsy samples is crucial for cancer treatment and monitoring. This review evaluates primary label‐free isolation methods for capturing heterogeneous CTCs and examines their potential to provide deeper insights into tumor heterogeneity and dynamics of cancer progression.
Gürhan Özkayar, Esma Derin, Georg R. Pesch, John W. M. Martens, Peter ten Dijke, Pouyan E. Boukany   +5 more
wiley   +1 more source

Mitophagy: A novel perspective for insighting into cancer and cancer treatment

Cell Proliferation, Volume 55, Issue 12, December 2022., 2022
Mitophagy is a physiological process regulated by complex and diverse mechanisms. Here we summarize the 15 main molecular mechanisms involved in the mammalian mitophagy processes and some potential anticancer drugs targeting mitophagy. Abstract Background Mitophagy refers to the selective self‐elimination of mitochondria under damaged or certain ...
Congkuan Song, Shize Pan, Jinjin Zhang, Ning Li, Qing Geng   +4 more
wiley   +1 more source

Plum pudding random medium model of biological tissue toward remote microscopy from spectroscopic light scattering [PDF]

Biomed. Opt. Express 8, 2879-2895 (2017), 2017
Biological tissue has a complex structure and exhibits rich spectroscopic behavior. There is \emph{no} tissue model up to now able to account for the observed spectroscopy of tissue light scattering and its anisotropy. Here we present, \emph{for the first time}, a plum pudding random medium (PPRM) model for biological tissue which succinctly describes ...
arxiv   +1 more source