Results 71 to 80 of about 103,945 (310)

Digital morphometry illustrates a relationship between percentage of ductal carcinoma in-situ in breast needle core biopsy and margin status at lumpectomy

Journal of Pathology Informatics
Candidates for breast conserving surgery are selected based on imprecise variables and there is uncertainty surrounding the risk of complicated margins.
Alexander R. Gross, Gerald R. Hobbs, Jr., Luis Samayoa, Stell Santiago   +3 more
doaj   +1 more source

Carcinoma ductal in situ arising in a fibroadenoma: report of a rare case

Revista Médica de Minas Gerais, 2021
Although fibroadenoma is one of the most common lesions of the breast, its correlation with malignant changes is rare. When it occurs, the clinical presentation is similar to typical fibroadenomas, anatomopathological diagnosis is after surgery and ...
Jácome, Anna Carolina Pereira, Pinto, Bárbara Mendes, Mourão, Érika Monteiro Pinheiro, Beraldo, Fábia Silveira, Santos, Luís Cláudio   +4 more
doaj   +1 more source

Strawberry Notch 1 Acts as a Transcriptional Regulator Driving Oncogenic Programs in Liver Carcinogenesis

Advanced Science, EarlyView.
This study reports that SBNO1 protein is upregulated in several cancer entities. SBNO1 protein interacts with the basal transcription factor TFIID via TAF4, enabling its recruitment to transcription start sites and the modulation of target gene expression.
Sarah Fritzsche, Raisatun Nisa Sugiyanto, Kira Gür, Alina Krumme, Maxime Le Marois, Angelika Fraas, Aslihan Inal, Mario Huerta, Vanessa Henriques, Eva Eiteneuer, Thomas Albrecht, Alphonse Charbel, Michael T. Dill, Carsten Sticht, Carolina De La Torre, Stefan Pusch, Arianeb Mehrabi, Kai Breuhahn, Junfang Ji, Peter Schirmacher, Benjamin Goeppert, Stephanie Roessler   +21 more
wiley   +1 more source

Diagnostic pitfall in a case of ductal carcinoma-in situ with microinvasion

Journal of Cytology, 2016
We report a case of microinvasive carcinoma of the breast cytologically diagnosed as ductal carcinoma - in situ in an 80-year-old lady with a breast lump. Extensive sampling of mastectomy specimen showed ductal carcinoma in situ (DCIS). Many ducts showed
Yasmin A Momin, Medha P Kulkarni, Bhakti D Deshmukh, Kalpana R Sulhyan   +3 more
doaj   +1 more source

Expression of PIK3CA mutant E545K in the mammary gland induces heterogeneous tumors but is less potent than mutant H1047R. [PDF]

, 2013
The phosphoinositide 3-kinase (PI3K) signaling cascade is a key mediator of cellular growth, survival and metabolism and is frequently subverted in human cancer.
Bentires-Alj, M, Brinkhaus, H, Cardiff, Robert, Klebba, I, Koren, S, Leroy, C, Meyer, D, Müller, M, Müller, U   +8 more
core   +2 more sources

Mitochondrial Calcium Uniporter Drives Chemoresistance in Pancreatic Cancer via Glutathione‐Mediated Stemness Maintenance

Advanced Science, EarlyView.
PDAC has a poor prognosis due to chemoresistance. We revealed that MCU upregulation is associated with chemoresistance and stemness in PDAC. MCU‐mediated Ca2+ influx induced ER stress, activating the PERK‐ATF4/NRF2 axis to enhance PSAT1/SLC711 expression and glutathione synthesis, reducing ROS and maintaining stemness.
Zekun Li, Chenyang Meng, Guangcong Shen, Yueying Shan, Junjin Wang, Diliyaer Abudukeremu, Rui Zhao, Bo Ni, Chao Xu, Xiaofan Guo, Jun Yu, Kaiyuan Wang, Shengyu Yang, YunZhan Li, Yongjie Xie, Tianxing Zhou, Jihui Hao, Xiuchao Wang   +17 more
wiley   +1 more source

Ductal carcinoma in situ

, 2012
Ductal carcinoma in situ (DCIS) represents a spectrum of abnormal cells confined to the breast and is a risk factor for invasive cancer development. The incidence has increased dramatically in recent years as a result of widespread use of screening mammography.
Nuran Senel Bese, Ayfer Ay
  +5 more sources

Factores predictivos de invasión en carcinoma ductal in situ diagnosticado por biopsia con aguja de corte

Cirugía y Cirujanos, 2022
Objetivo: Identificar características clínicas, radiológicas e histopatológicas como factores predictivos de carcinoma mamario microinvasor/invasor en pacientes con Carcinoma Ductal In Situ (CDIS) diagnosticado mediante aguja de corte. Material y métodos:
Felipe Villegas-Carlos, Verónica Andino-Araque, Margarita Valverde-Quintana, Kictzia Y. Larios-Cru, Yosef Pérez-González, Juan J. Solano-Pérez, Eva Ruvalcaba-Limón   +6 more
doaj   +1 more source

A novel therapy for breast cancer: implications for treatment access [PDF]

, 2019
In 2016, there were 250,000 new cases of invasive cancer and 60,000 of ductal carcinoma in situ. Mammograms are used to screen for cases of disease, but the literature shows that mammograms are highly dependent on patient characteristics and do not ...
Cespedes-Gomez, Omar
core  

Turbo Spin-echo Diffusion-weighted Imaging Compared with Single-shot Echo-planar Diffusion-weighted Imaging: Image Quality and Diagnostic Performance When Differentiating between Ductal Carcinoma in situ and Invasive Ductal Carcinoma

Magnetic Resonance in Medical Sciences, 2020
Purpose: To compare the image quality between turbo spin-echo (TSE)-diffusion weighted imaging (DWI) and single-shot echo-planar imaging (EPI)-DWI, and to verify the diagnostic performance of the apparent diffusion coefficient (ADC) parameters of the two
N. Mori, S. Mugikura, M. Miyashita, Yu Mori, Yui Maekawa, T. Nagasaka, K. Takase   +6 more
semanticscholar   +1 more source