Results 51 to 60 of about 85,355 (254)

Targeting m6A Reader YTHDF1 Enhances Antitumor Immunity and Potentiates Anti‐PD‐L1 Efficacy in Intrahepatic Cholangiocarcinoma

open access: yesAdvanced Science, EarlyView.
The m6A reader YTHDF1 drives intrahepatic cholangiocarcinoma (ICC) progression by remodeling the tumor immune microenvironment. YTHDF1 promotes MDSC recruitment via activation of m6A‐FOSL2‐CXCL6/CXCR2 axis, thereby suppressing CD8+ T cell infiltration and function.
Li Luo   +14 more
wiley   +1 more source

Diagnostic pitfall in a case of ductal carcinoma-in situ with microinvasion

open access: yesJournal of Cytology, 2016
We report a case of microinvasive carcinoma of the breast cytologically diagnosed as ductal carcinoma - in situ in an 80-year-old lady with a breast lump. Extensive sampling of mastectomy specimen showed ductal carcinoma in situ (DCIS). Many ducts showed
Yasmin A Momin   +3 more
doaj   +1 more source

Carcinoma ductal in situ arising in a fibroadenoma: report of a rare case

open access: yesRevista Médica de Minas Gerais, 2021
Although fibroadenoma is one of the most common lesions of the breast, its correlation with malignant changes is rare. When it occurs, the clinical presentation is similar to typical fibroadenomas, anatomopathological diagnosis is after surgery and ...
Jácome, Anna Carolina Pereira   +4 more
doaj   +1 more source

A novel therapy for breast cancer: implications for treatment access [PDF]

open access: yes, 2019
In 2016, there were 250,000 new cases of invasive cancer and 60,000 of ductal carcinoma in situ. Mammograms are used to screen for cases of disease, but the literature shows that mammograms are highly dependent on patient characteristics and do not ...
Cespedes-Gomez, Omar
core  

Thyroid transcription factor-1 positive primary breast cancer: a case report with review of the literature [PDF]

open access: yes, 2010
This case describes an infiltrating breast tumour with thyroid transcription factor-1 (TTF-1) positive staining and ductal differentiation in a 72-year-old woman.
Klingen, Tor A   +5 more
core   +1 more source

Integrating Spatial Proteogenomics in Cancer Research

open access: yesAdvanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang   +13 more
wiley   +1 more source

Ductal carcinoma in situ

open access: yes, 2012
Ductal carcinoma in situ (DCIS) represents a spectrum of abnormal cells confined to the breast and is a risk factor for invasive cancer development. The incidence has increased dramatically in recent years as a result of widespread use of screening mammography.
Nuran Senel Bese, Ayfer Ay
  +5 more sources

Pharmacokinetic Analysis of Gd-DTPA Enhancement in dynamic three-dimensional MRI of breast lesions [PDF]

open access: yes, 1997
The purpose of this study was to demonstrate that dynamic MRI covering both breasts can provide sensitivity for tumor detection as well as specificity and sensitivity for differentiation of tumor malignancy.
de Vos, Rob A.I.   +10 more
core   +4 more sources

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

open access: yesAdvanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu   +8 more
wiley   +1 more source

An atypical presentation of infiltrating ductal carcinoma

open access: yesJournal of Family Medicine and Primary Care, 2016
A 64-year-old African-American female presented with nonbloody nipple discharge. Clinical and cytological examination of the discharge was normal. The mammography suggested pleomorphic calcification in the left breast. A stereotactic biopsy showed ductal
Kunal Kishor Jha, Suresh Kumar Gupta
doaj   +1 more source

Home - About - Disclaimer - Privacy