Results 41 to 50 of about 85,355 (254)

A Juvenile Female with Ductal Carcinoma In situ Arising from a Fibroadenoma

Journal of Cancer Research and Practice, 2023
Ductal carcinoma in situ (DCIS) and atypical ductal hyperplasia are rare in teenagers. We report an incidental finding of DCIS in a 17-year-old girl who presented with a mass in the right breast. The pathology confirmed lower-grade DCIS in a fibroadenoma.
Wan-Yu Hung, Chih-Ling Lee, Chin-Yao Lin
doaj   +1 more source

Macrophages promote the progression of premalignant mammary lesions to invasive cancer. [PDF]

, 2017
Breast cancer initiation, progression and metastasis rely on a complex interplay between tumor cells and their surrounding microenvironment. Infiltrating immune cells, including macrophages, promote mammary tumor progression and metastasis; however, less
Anderson, Bissell, Blair, Colombatti, Colombo, Condeelis, Coussens, De Palma, Earp, Ghosh, Green, Gunaratne, Hermoso, Hylton, Jensen, Jirstrom, Lewis, Lidereau, Luo, Lydon, Maatta, Machado, Mantovani, Naber, Naldini, Ochiai, Ochoa, Piemonti, Pollard, Pollard, Pollard, Pollard, Pollard, Porse, Rosen, Rosen, Rosen, Sarukhan, Schwertfeger, Schwertfeger, Shen, Strassmann, Suthipintawong, Ullrich, Van Ginderachter, Van Ginderachter, van Rooijen, Visvader, Wang, West   +49 more
core   +1 more source

Protein expression of c-erbB-2 and p53 in normal ducts, ductal carcinoma in situ and invasive carcinoma of the same breast

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Breast cancer is thought to derive from progressively aberrant, non-invasive breast lesions, but it is not known exactly how invasive breast cancer develops from these lesions.
Marcus Vinicius Martins de Menezes, Anna Letícia Oliveira Cestari, Orlando Almeida, Marcelo Alvarenga, Glauce Aparecida Pinto, Maria Salete Costa Gurgel, Gustavo Antônio de Souza, Luiz Carlos Zeferino   +7 more
doaj   +1 more source

Importance of microcalcifications in mammographic differentiation of the invasive ductal breast cancer and of the ductal carcinoma in situ [PDF]

Medicinski Podmladak, 2017
Introduction: Microcalcifications represent a significant and reliable sign of the presence of the malignant breast lesion. Aim: The aim of the paper is to radiologically evaluate the type and distribution of suspicious microcalcifications, in patients ...
Šarac Vanja, Nadrljanski Mirjan
doaj  

Importância da segunda opinião em patologia cirúrgica mamária e suas implicações terapêuticas Importance of a second opinion in breast surgical pathology and therapeutic implications

Revista Brasileira de Ginecologia e Obstetrícia, 2008
OBJETIVO: avaliar a concordância dos diagnósticos histopatológicos de lesões mamárias entre patologistas da comunidade e especialista em patologia mamária.
Márcio de Almeida Salles, Fernanda Squarcio Fernandes Sanches, Amanda Arantes Perez, Helenice Gobbi   +3 more
doaj   +1 more source

Key signalling nodes in mammary gland development and cancer: the snail1-twist1 conspiracy in malignant breast cancer progression [PDF]

, 2010
Breast cancer is the most common cancer among women, and despite significant advances in diagnosing and treating it, metastatic spread of cancer cells results in a high mortality rate. Epithelial-to-mesenchymal transition (EMT) is an embryonic program in
Foubert, Ellen, De Craene, Bram, Berx, Geert   +2 more
core   +2 more sources

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

Digital morphometry illustrates a relationship between percentage of ductal carcinoma in-situ in breast needle core biopsy and margin status at lumpectomy

Journal of Pathology Informatics
Candidates for breast conserving surgery are selected based on imprecise variables and there is uncertainty surrounding the risk of complicated margins.
Alexander R. Gross, Gerald R. Hobbs, Jr., Luis Samayoa, Stell Santiago   +3 more
doaj   +1 more source

Factores predictivos de invasión en carcinoma ductal in situ diagnosticado por biopsia con aguja de corte

Cirugía y Cirujanos, 2022
Objetivo: Identificar características clínicas, radiológicas e histopatológicas como factores predictivos de carcinoma mamario microinvasor/invasor en pacientes con Carcinoma Ductal In Situ (CDIS) diagnosticado mediante aguja de corte. Material y métodos:
Felipe Villegas-Carlos, Verónica Andino-Araque, Margarita Valverde-Quintana, Kictzia Y. Larios-Cru, Yosef Pérez-González, Juan J. Solano-Pérez, Eva Ruvalcaba-Limón   +6 more
doaj   +1 more source

A proteomic approach to identify endosomal cargoes controlling cancer invasiveness [PDF]

, 2017
We have previously shown that Rab17 - a small GTPase associated with epithelial polarity - is specifically suppressed by ERK2 signalling to promote an invasive phenotype.
Diaz-Vera, Jesica, Dornier, Emmanuel, Edwards, Joanne, Hernandez-Fernaud, Juan Ramon, MacPherson, Iain, Mitchell, Louise E., Norman, Jim C., Palmer, Sarah, Zanivan, Sara   +8 more
core   +2 more sources