Objective To determine the clinicopathological features and prognostic differences between ductal carcinoma in situ (DCIS) and ductal carcinoma in situ with microinvasion (DCIS-MI) of breast cancer. Methods A cohort of 489 female patients with surgically
LIU Jing +4 more
doaj +1 more source
Atypical Ductal Hyperplasia at the Margin of Lumpectomy Performed for Early Stage Breast Cancer: Is there Enough Evidence to Formulate Guidelines? [PDF]
Background. Negative margins are associated with a reduced risk of ipsilateral breast tumor recurrence (IBTR) in women with early stage breast cancer treated with breast conserving surgery (BCS).
Baker, Jennifer L +2 more
core +3 more sources
Evaluation of a Novel Anti-Mucin 1 (MUC1) Antibody (PankoMab) as a Potential Diagnostic Tool in Human Ductal Breast Cancer; Comparison with Two Established Antibodies [PDF]
Aim: PankoMab is a novel antibody that recognizes a tumor-specific epitope of Mucin 1 (MUC1). The aim of this study was the evaluation of PankoMab as a potential diagnostic tool and its comparison with two established antibodies against MUC1 in human ...
Dian, Darius +7 more
core +1 more source
Adenocarcinoma in situ (ductal type) ex pleomorphic adenoma of the lacrimal gland
Purpose: To present the clinical and histopathological characteristics of a rare case of ductal carcinoma in situ ex pleomorphic adenoma in the lacrimal gland.
Zainab Fakhril-din +4 more
doaj +1 more source
Breast cancer or metastasis? An unusual case of metastatic malignant pleural mesothelioma to the breast [PDF]
Background: Metastases to the breast from extramammary malignancies are very rare, and ruling out the diagnosis of primary breast tumor is important in order to decide on clinical management and predict prognosis.
Derme, Martina +5 more
core +2 more sources
Ductal carcinoma in situ revisited
Since our review appeared in The Breast, further information from randomized studies has become available. The EORTC data have been published and are summarized in Table 1. This was a randomized trial assessing the value of radiotherapy after breast conserving surgery.
J M, Dixon, D L, Page
openaire +2 more sources
Objective: Population-wide mammographic screening programs aim to reduce breast cancer mortality. However, a broad view of the harms and benefits of these programs is necessary to favor informed decisions, especially in the earliest stages of the disease.
Julieta Politi +6 more
doaj +1 more source
Words do matter:A systematic review on how different terminology for the same condition influences management preferences [PDF]
OBJECTIVES: Changing terminology for low-risk, screen-detected conditions has now been recommended by several expert groups in order to prevent overdiagnosis and reduce the associated harms of overtreatment. However, the effect of terminology on patients'
Barratt, Alexandra L +4 more
core +1 more source
Can Molecular Biomarkers Help Reduce the Overtreatment of DCIS?
Ductal carcinoma in situ (DCIS), especially in the era of mammographic screening, is a commonly diagnosed breast tumor. Despite the low breast cancer mortality risk, management with breast conserving surgery (BCS) and radiotherapy (RT) is the prevailing ...
Ezra Hahn +6 more
doaj +1 more source
The expression pattern of MUC1 (EMA) is related to tumour characteristics and clinical outcome of invasive ductal breast carcinoma [PDF]
Aims: To clarify MUC1 patterns in invasive ductal breast carcinoma and to relate them to clinicopathological parameters, coexpression of other biological markers and prognosis.
Arnerlov C +10 more
core +2 more sources

