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Ductal carcinoma in situ of the breast [PDF]
#### Summary points Ductal carcinoma in situ (DCIS) is a preinvasive (also termed non-invasive) breast cancer, where proliferations of malignant ductal epithelial cells remain confined within intact breast ducts (fig 1⇓). DCIS is a precursor lesion that has the potential to transform into an invasive cancer over a timescale that may be a few years or ...
Nicola L P, Barnes +3 more
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Additional file 1 of Potential biomarkers of ductal carcinoma in situ progression
Additional file 1: Table S1. Comparison between control and pure invasive ductal carcinoma. Differentially expressed genes are in bold. Table S2. Comparison between control and pure ductal carcinoma in situ.
Elaine Stur (507776) +17 more
core +1 more source
Epidemiology of Ductal Carcinoma In Situ [PDF]
Ductal carcinoma in situ (DCIS) is a relatively common diagnosis among women undergoing screening mammography. The greatest increases in DCIS incidence have been in non-comedo subtypes of DCIS that are not associated with subsequent invasive cancer. After a 500% increase in DCIS from 1983 to 2003, the incidence of DCIS declined in women aged 50 years ...
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Objective: Population-wide mammographic screening programs aim to reduce breast cancer mortality. However, a broad view of the harms and benefits of these programs is necessary to favor informed decisions, especially in the earliest stages of the disease.
Julieta Politi +6 more
doaj +1 more source
Adenocarcinoma in situ (ductal type) ex pleomorphic adenoma of the lacrimal gland
Purpose: To present the clinical and histopathological characteristics of a rare case of ductal carcinoma in situ ex pleomorphic adenoma in the lacrimal gland.
Zainab Fakhril-din +4 more
doaj +1 more source
Ductal Carcinoma In Situ: Pathology
Ductal carcinomata in situ (DCIS) are both biologically and morphologically a heterogeneous group of neoplastic intraductal proliferations of the breast tissue, they represent an important precursor lesion for the development of invasive breast carcinoma and their diagnosis increases due to improved imaging.
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Breast Ductal Carcinoma In Situ [PDF]
Ductal carcinoma in situ (DCIS) of the breast is becoming one of the most important diseases diagnosed in preventive medicine screening. The current age-adjusted incidence rate of DCIS is 32.5 per 100,000 women. For women 50–64 years of age, the incidence is approximately 88 per 100,000. Currently, for every 4 diagnoses of invasive breast cancer, there
Sacchini, Virgilio +5 more
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Supplementary Figure S2 shows the repertoire and number of non-synonymous somatic mutations and mutational signatures in synchronously diagnosed ductal carcinoma in situ and invasive ductal carcinoma of no special type and in pure ductal carcinoma in ...
David N. Brown (6742649) +15 more
core +1 more source
Can Molecular Biomarkers Help Reduce the Overtreatment of DCIS?
Ductal carcinoma in situ (DCIS), especially in the era of mammographic screening, is a commonly diagnosed breast tumor. Despite the low breast cancer mortality risk, management with breast conserving surgery (BCS) and radiotherapy (RT) is the prevailing ...
Ezra Hahn +6 more
doaj +1 more source
Ductal carcinoma in situ revisited
Since our review appeared in The Breast, further information from randomized studies has become available. The EORTC data have been published and are summarized in Table 1. This was a randomized trial assessing the value of radiotherapy after breast conserving surgery.
J M, Dixon, D L, Page
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