Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC
Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu +11 more
wiley +1 more source
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis. Abstract Background and Aims Nucleotide‐binding oligomerization domain‐like receptor‐family pyrin domain‐containing 3 (NLRP3) inflammasome activation has been shown to result in liver fibrosis.
Jana Knorr +19 more
wiley +1 more source
Purpose To predict ductal carcinoma in situ with microinvasion (DCISMI) based on clinicopathologic, conventional breast magnetic resonance imaging (MRI), and dynamic contrast enhanced MRI (DCE-MRI) radiomics signatures in women with biopsy-confirmed ...
Zhou Huang +4 more
doaj +1 more source
Cystic hypersecretory carcinoma with invasion: Case series on a rare variant of carcinoma breast
Background: Cystic Hypersecretory Carcinoma (CHC) is a rare subset of breast carcinoma. It is part of a spectrum of cystic hypersecretory lesions which includes cystic hypersecretory hyperplasia (CHH), CHH with atypia, CHC in situ and CHC with invasion ...
Hibu Yami +3 more
doaj +1 more source
Does Existence of Ductal Carcinoma In Situ Accompanying Invasive Ductal Carcinoma Lead to Different Clinicopathological Features and Clinical Outcome? Report of a Breast Cancer Registry [PDF]
Background: Ductal carcinoma in situ (DCIS) is widely recognized as the precursor of invasive ductal carcinoma (IDC). We aimed to compare clinicopathological characteristics and prognosis between IDC with and without coexisting DCIS stratified by ...
Sedigheh Tahmasebi +7 more
doaj +1 more source
The Baader-Meinhof phenomenon in ductal carcinoma in situ of the breast [PDF]
Sir: We read with interest the review of Pang et al. published in the annual review issue of Histopathology in January 2016, entitled ‘Ductal carcinoma in situ—update on risk assessment and management’, wherein a concise overview of the diagnosis and ...
Floris, Giuseppe +3 more
core +2 more sources
Predicting invasive breast cancer versus DCIS in different age groups. [PDF]
BackgroundIncreasing focus on potentially unnecessary diagnosis and treatment of certain breast cancers prompted our investigation of whether clinical and mammographic features predictive of invasive breast cancer versus ductal carcinoma in situ (DCIS ...
Alagoz, Oguzhan +7 more
core +1 more source
Clinical-pathological features of an occult mixed mucinous male breast cancer. a case report [PDF]
Mucinous carcinoma of the male breast is an uncommon malignant breast neoplasm and its diagnoses remain difficult. It is probably due to such a low rate of breast cancer cases that men tend to be diagnosed at an older age than women and with a later ...
Bonifacino, Adriana +7 more
core +1 more source
Ductal Carcinoma In Situ: Pathology
Ductal carcinomata in situ (DCIS) are both biologically and morphologically a heterogeneous group of neoplastic intraductal proliferations of the breast tissue, they represent an important precursor lesion for the development of invasive breast carcinoma and their diagnosis increases due to improved imaging.
openaire +2 more sources
Independent predictors of breast malignancy in screen-detected microcalcifications: biopsy results in 2545 cases [PDF]
Background: Mammographic microcalcifications are associated with many benign lesions, ductal carcinoma in situ (DCIS) and invasive cancer. Careful assessment criteria are required to minimise benign biopsies while optimising cancer diagnosis.
Downey, P. +4 more
core +2 more sources

