Results 161 to 170 of about 22,800,094 (304)

Retraction: Gamification of Incentive Spirometry in Trauma Patients: Protocol for a Prospective, Observational Feasibility Study. [PDF]

JMIR Res Protoc
JMIR Publications Editorial Office.
europepmc   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

A multisectoral approach to developing a national strategy for mental health and suicide prevention in Sweden. [PDF]

Glob Health Action
Becker L, Biermann O, Östergren PO, Holsbrink S, Sundewall J.   +4 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Student Perceptions of Obstacles in Science Careers are Not Altered by Scientist Stories of Challenges. [PDF]

CBE Life Sci Educ
Prathibha P, Driessen EP, Kjelvik MK, Schultheis EH, Zemenick AT, Weber MG, Ballen CJ, Costello RA.   +7 more
europepmc   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Sterilization; Due Process; Immunity; MR

, 2001

core  

Fatigue and Driving Safety in Early Parenthood: Developing Feasible Risk-Reduction Strategies Through Co-Design. [PDF]

Health Promot J Austr
Sprajcer M, Kovac K, Thomas MJW, Ferguson SA, Gupta CC, Bachmann A, Miller DJ, Thorne H, Bishop BC, Vincent GE.   +9 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Sergei Kovalev: Biologist Denied Due Process and Medical Care

, 1976
Wade, Nicholas
core   +1 more source