Results 121 to 130 of about 481,402 (359)

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons, Marc A. Beal, Kerry L. Dearfield, George R. Douglas, Min Gi, B. Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Michelle Kenyon, Alexandra S. Long, David P. Lovell, Anthony M. Lynch, Meagan B. Myers, Stefan Pfuhler, Alisa Vespa, Andreas Zeller, George E. Johnson, Paul A. White   +17 more
wiley   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Increased incidence, survival, and registration quality of primary hepato‐pancreato‐biliary cancers in the Netherlands Cancer Registry

International Journal of Cancer, EarlyView.
What's New? Primary hepato‐pancreato‐biliary cancers have poor prognosis and their reporting often scores low on standard data quality indicators in population‐based cancer registries. This comprehensive evaluation of cases in the Netherlands Cancer Registry shows that both the incidence and survival rates of most primary hepato‐pancreato‐biliary ...
Lydia G. van der Geest, Marianne van der Mark, Joanne Verheij, Arantza Farina Sarasqueta, Judith de Vos‐Geelen, Marc G. Besselink, Vincent E. de Meijer, Ignace H. J. T. de Hingh, Bert A. Bonsing, Philip R. de Reuver, Francois E. J. A. Willemssen, Pauline A. J. Vissers, Otto Visser, the Dutch Pancreatic Cancer Group and the Dutch Hepatocellular & Cholangiocarcinoma Group   +13 more
wiley   +1 more source

Duodenum‐preserving total pancreatectomy for pancreatic neoplasms [PDF]

, 2009
Takashi Hatori, Akira Kimijima, Izumi Fujita, Toru Furukawa, Masakazu Yamamoto   +4 more
openalex   +1 more source

Recurrent Malignant Duodenal Neoplasm [PDF]

, 2020

openalex   +1 more source

Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol

International Journal of Cancer, EarlyView.
What's New? PARP inhibitors are effective in patients with inactivating alterations in the BRCA1/2 genes across tumor types. However, the efficacy of PARP inhibitors in patients with other inactivated homologous recombination repair genes remains unclear. This knowledge gap and discrepancies in EMA/FDA approvals highlight the need for better biomarkers.
Ilse A. C. Spiekman, Niven Mehra, Laurien J. Zeverijn, Birgit S. Geurts, Karlijn Verkerk, Soemeya F. Haj Mohammad, Vincent van der Noort, Paul Roepman, Wendy W. J. de Leng, Anne M. L. Jansen, Addy C. M. van de Luijtgaarden, Theo van Voorthuizen, Tineke E. Buffart, Hans Gelderblom, Emile E. Voest, Henk M. W. Verheul   +15 more
wiley   +1 more source

Utility of underwater endoscopic mucosal resection combined with a protruding anchor by saline injection for superficial non-ampullary duodenal tumors: a retrospective study in Japan [PDF]

Clinical Endoscopy
Background/Aims Underwater endoscopic mucosal resection (UEMR) is the standard resection method for superficial non-ampullary duodenal tumors (SNADETs).
Yoshie Nomoto, Satoshi Shinozaki, Yoshimasa Miura, Hiroyuki Osawa, Yuji Ino, Tomonori Yano, Nikolaos Lazaridis, Hironori Yamamoto   +7 more
doaj   +1 more source

Two case of bilateral approach in laparoscopic pancreas-sparing distal duodenectomy for duodenal neoplasms arising from the distal duodenum. [PDF]

Int J Surg Case Rep, 2021
Nagano H, Yoshimura F, Shimaoka H, Maki K, Yoshimatsu G, Hasegawa S.   +5 more
europepmc   +1 more source

609 Endoscopic Management of Duodenal Neoplasms and Factors Leading to Incomplete Resection and Recurrence: Where Are We Now? [PDF]

, 2011
Reem Z. Sharaiha, Susana Gonzalez, Christopher Ramos, Amrita Sethi, John M. Poneros, Harold Frucht, Peter D. Stevens   +6 more
openalex   +1 more source

Mortality study of 18 000 patients treated with omeprazole. [PDF]

, 2002
Background: The long term safety of potent gastric acid suppressive therapy has yet to be established. Method: General practice record review at a median interval of 26 months followed by retrieval of details of all deaths within four years using the ...
Bateman, D.N., Colin-Jones, D., Hartz, S., Langman, M., Logan, R.F., Mant, J.W.F., Murphy, M, Paterson, K.R., Rowsell, R., Thomes, S.   +9 more
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