Results 51 to 60 of about 171,025 (297)

Erzincan Mengücek Gazi Eğitim ve Araştırma Hastanesi’nde 2010-2018 Yılları Arasında Tanı Alan Erişkin Çölyak Hastalarının Değerlendirilmesi

open access: yesSakarya Tıp Dergisi, 2020
Amaç: Erzincan Mengücek Gazi Eğitim ve Araştırma Hastanesi’nde 2010-2018 yılları arasında tanı alan 18 yaş üstü erişkin Çölyak hastalarını değerlendirmek.
Mahir Tayfur
doaj   +1 more source

Zinc Alleviates Gut Barrier Dysfunction by Promoting the Methylation of AKT

open access: yesAdvanced Science, EarlyView.
Zinc activates the ZNG1‐METAP1 complex to elevate intracellular SAM levels, which promotes PRMT5‐mediated symmetrical dimethylation of AKT at R391 and R15. This epigenetic modification facilitates AKT membrane translocation and mTORC2 activation, thereby enhancing epithelial proliferation and gut barrier integrity.
Chuanjiang Cai   +13 more
wiley   +1 more source

Comparative Single‐Cell Transcriptomic Landscape Reveals the Regulatory Mechanisms of Lactation during Selective Breeding in Asian Water Buffalo

open access: yesAdvanced Science, EarlyView.
In this study, a comprehensive single‐cell transcriptome atlas of river and swamp buffalo, encompassing 12 tissues and 397,011 cells, is constructed. Differential expression analyses identify metabolic and secretory tissues and cell types that mediate the divergence of milk production.
Dongmei Dai   +13 more
wiley   +1 more source

A history of gastrectomy is a risk factor for choledocholithiasis in patients undergoing cholecystectomy: A single center retrospective study

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This retrospective study suggests that gastrectomy is a risk factor for choledocholithiasis. Especially in terms of the differences in reconstruction methods, the median time from gastrectomy to development of choledocholithiasis was 5.5 years for Roux‐en‐Y, which was significantly faster than 20 years for Billroth I and 35 years for Billroth II ...
Yuki Matsui   +8 more
wiley   +1 more source

Intestinal peroxisome proliferator‐activated receptor α‐fatty acid‐binding protein 1 axis modulates nonalcoholic steatohepatitis

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Peroxisome proliferator‐activated receptor α (PPARα) regulates fatty acid transport and catabolism in liver. However, the role of intestinal PPARα in lipid homeostasis is largely unknown. Here, intestinal PPARα was examined for its modulation of obesity and NASH. Approach and Results Intestinal PPARα was activated and fatty
Tingting Yan   +22 more
wiley   +1 more source

Long‐Term Nutritional Benefits of Laparoscopic Pancreatoduodenectomy Over Open Surgery

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Minimally invasive laparoscopic pancreaticoduodenectomy (LPD) significantly improves long‐term nutritional outcomes compared to open pancreaticoduodenectomy (OPD). LPD patients demonstrated better preservation of muscle mass index (PMI) and a lower incidence of postoperative fatty liver.
Koki Kurahashi   +9 more
wiley   +1 more source

CD8+ T cell memory is sustained in mice by hepatic stellate cells

open access: yesHepatology, EarlyView., 2022
HSC role in memory CD8+ T cell maintenance. Abstract Background and Aims Long‐lasting immunological memory is the ultimate goal of vaccination. Homeostatic maintenance of memory CD8+ cytotoxic T cells (MemCD8TCs) is thought to be mediated by IL‐15/IL‐15R heterodimer (15HD)‐expressing myeloid cells.
Yi‐Ting Chen   +4 more
wiley   +1 more source

External Validation of an Automated Surgical Step Recognition Model for Robotic Distal Gastrectomy (RDG) Using a Multicenter Dataset

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Our present study reveals that surgical step recognition performs moderately well when trained on video data from a single institution and applied to an external institution's data. Nevertheless, our model substantially improves its prediction capabilities when trained on the same amount of data from multiple institutions.
James S. Strong   +8 more
wiley   +1 more source

Blood in the Duodenum [PDF]

open access: yesGastroenterology, 2020
Cassandra Duarte, Nanxing Li
openaire   +3 more sources

Impact of Ghrelin‐Depleting Gastrectomy on Long‐Term Endocrine and Metabolic Health With a Focus on Skeletal Muscle and Bone Mineral Content

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
This study investigates the long‐term endocrine and metabolic consequences of ghrelin‐depleted gastrectomy, with a focus on skeletal muscle mass and bone mineral content. Sustained reductions in serum desacyl‐ghrelin were linked to lower IGF‐1 levels, resulting in significant loss of muscle and bone.
Hiroki Harada   +9 more
wiley   +1 more source

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