Results 71 to 80 of about 149,629 (303)

A Novel Reactive Oxygen Species‐Responsive Bone‐Targeted Nanoplatform Based on Cloperastine Attenuates Ovariectomy‐Induced Bone Loss by Inhibiting Osteoclast Oxidative Phosphorylation

Advanced Science, EarlyView.
Cloperastine suppresses osteoclastogenesis by inhibiting PGC1β‐mediated oxidative phosphorylation. Its incorporation into a ROS‐responsive, Asp8‐modified nanoplatform enhances skeletal accumulation. The resulting Clo/Asp8‐PMK‐MCs combine cloperastine‐mediated antiresorptive activity with carrier‐mediated osteogenic activity to attenuate OVX‐induced ...
Haibo Liang, Yong Xiao, Jiangtao Luo, Xiao Yang, Yayun Yang, Qihang Wu, Chenxin Yu, Zhihao Zhou, Xiaoqing Si, Jiansen Miao, Yiting Tu, Qichen Lu, Boreng Qian, Xiangyang Wang, Jiake Xu, Changcan Shi, Haiming Jin   +16 more
wiley   +1 more source

Case Report-Mega-duodenum due to isolated segmental duodenal aganglionosis [PDF]

, 2007
Isolated segmental duodenal aganglionosis is an extremely rare condition. We report a case of mega-duodenum due to an isolated aganglionic segment in the second part of the duodenum. A 60-year-old female presented with a history of off-and-on non-bilious
Barmeda, Shailesh H., Porecha, Mehul M.
core   +3 more sources

Abdominal compartment syndrome from bleeding duodenal diverticulum

Journal of Emergencies, Trauma and Shock, 2012
Duodenal diverticuli are acquired false diverticuli of unknown etiology. Although mostly asymptomatic, they can occasionally cause upper gastrointestinal hemorrhage, rarely with massive bleeding.
Vakhtang Tchantchaleishvili, Shawn S Groth, Jorge A Leon, William J Mohr   +3 more
doaj   +1 more source

Artificial Intelligence–Based Surgical Phase Analysis Enables Objective Assessment of Surgeon Skill in Robotic Distal Gastrectomy: A Multicenter Study

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Artificial intelligence (AI)–based surgical video analysis can automate time‐consuming manual assessments and enable objective characterization of surgical workflows. We aimed to construct a large, multicenter, fully annotated dataset of robotic distal gastrectomy (RDG) videos and evaluate the feasibility and performance of an AI model for
Masaru Komatsu, Daichi Kitaguchi, Yoichi Ninomiya, Yuya Takabe, Mitsumasa Yoshida, Masahiro Yura, Nobuyoshi Takeshita, Takahiro Kinoshita, Masaaki Ito   +8 more
wiley   +1 more source

Duodenal neuroendocrine cells and neuromedin U in subjects with obesity: Relationship with type 2 diabetes and glucose homeostasis

Physiological Reports
Duodenal endocrine cells contribute to the incretin response, yet their changes in obesity and type 2 diabetes (T2D) remain controversial. We quantified expression of chromogranin A, glucagon‐like peptide‐1 (GLP‐1), serotonin, and neuromedin U (NmU) in ...
Hassan Bur, Janne Hukkanen, Markku J. Savolainen, Vesa Koivukangas, Tuomo J. Karttunen   +4 more
doaj   +1 more source

Effect of Cereal Contaminants on the Inflammation and Oxidative Stress in the Gut of Weanling Piglets

Scientific Papers Animal Science and Biotechnologies, 2023
Cereals and cereals-based products are frequently contaminated with ochratoxin A (OTA) and aristolochic acid (AA). The aim of this study was to compare the effect of OTA and AA on oxidative stress and inflammation in the swine intestine as major organ ...
Daniela Eliza Marin, Gina Cecilia Pistol, Mihai Gras, Mihai Palade, Ionelia Taranu   +4 more
doaj  

Dealing with the hugely ectatic duodenum in high jejunal atresias [PDF]

, 2018
High jejunal atresias may be associated with ectasia of the duodenum and dysmotility, which can delay inception of feedings and inanition. The procedures used for ectatic jejunum cannot be applied to the duodenum because of its complex anatomy.
Mazkary, Mufarrah H., Jetley, Nishith K., Syed, Muhammad, Al-Helal, Abdullah S.   +3 more
core   +1 more source

The comparative characteristic of pheno- and genotypical signs in neonates with atresia of duodenum and other parts of the small intestine

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2012
Aim of investigation. Analysis of phenotypical and genotypical signs in neonates with atresia of duodenum and other parts of the small intestine.Material and methods.
O. K. Botvin'yev, A. V. Eremeeva
doaj  

Impact of Histopathological Response on Outcomes After Surgical Resection Following Carbon‐Ion Radiotherapy for Pancreatic Cancer With Arterial Involvement

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim Carbon‐ion radiotherapy (CIRT) provides superior dose distribution and higher biological effectiveness than conventional X‐ray radiotherapy and has emerged as a promising component of multidisciplinary treatment for advanced pancreatic ductal adenocarcinoma (PDAC).
Kenichiro Araki, Norio Kubo, Yuhei Miyasaka, Hayato Ikota, Ryo Muranushi, Mariko Tsukagoshi, Takamichi Igarashi, Masahiko Okamoto, Tatsuya Ohno, Ken Shirabe   +9 more
wiley   +1 more source

Preventive Effect of Antioxidant From Purple Rosella Yoghurt on Duodenum and Colon Histopathology of Rattus norvegicus Exposed to Rhodamine B And Saccharin

Journal of Experimental Life Science
Rodhamine B and Saccharin are often misused by food producers as food additive, which, if their use is not monitored, can produce free radicals that cause oxidative stress conditions in the body, leading to dangerous damage to the body.
Ajeng Erika Prihastuti Haskito, Bintari Nariswari, Anna Safitri, Aldila Noviatri, Handayu Untari, Citra Sari   +5 more
doaj   +1 more source