OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta +4 more
wiley +1 more source
Vaccinating patients on biologics for atopic disease: Clinical considerations and evidence-based recommendations. [PDF]
Chase NM.
europepmc +1 more source
Dupilumab and cutaneous T-cell lymphoma: A retrospective cohort study. [PDF]
Baghdasarian S, Al-Saedi O, Cuomo RE.
europepmc +1 more source
Dupilumab in moderate‐to‐severe prurigo nodularis: Real‐world data from early access program
Journal of the European Academy of Dermatology and Venereology, EarlyView.
Marie Jachiet +14 more
wiley +1 more source
Immune system benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease
Abstract Chronic obstructive pulmonary disease (COPD) is a respiratory disease characterized by pulmonary and systemic inflammation. Inflammatory mediators show relationships with shortness of breath, exercise intolerance and health related quality of life. Pulmonary rehabilitation (PR), a comprehensive education and exercise training programme, is the
Asghar Abbasi +4 more
wiley +1 more source
The evaluation of the plasma levels of interleukin 17A, thymic stromal lymphopoietin, interferon gamma, tumor necrosis factor-alpha and interleukins IL-2, IL-6, IL-23, and IL-31 in atopic dermatitis patients with dupilumab treatment. [PDF]
Čelakovská J +3 more
europepmc +1 more source
ABSTRACT Eosinophilic esophagitis (EoE) is a chronic, immune‐mediated disease requiring long‐term therapy. Dupilumab, an interleukin‐4 and interleukin‐13 receptor antagonist, is approved for EoE at a weekly 300 mg dosing regimen. However, data on reduced‐frequency dosing, especially in pediatric patients, remain limited.
Giovanni Scatigna +4 more
wiley +1 more source
Dupilumab Improves Daily Symptom Burden in Adult Patients with Prurigo Nodularis: Post Hoc Analysis from LIBERTY PN-PRIME and PRIME2 Studies. [PDF]
Kwatra SG +9 more
europepmc +1 more source

