Meta-analysis derived atopic dermatitis (MADAD) transcriptome defines a robust AD signature highlighting the involvement of atherosclerosis and lipid metabolism pathways [PDF]
BACKGROUND: Atopic dermatitis (AD) is a common inflammatory skin disease with limited treatment options. Several microarray experiments have been conducted on lesional/LS and non-lesional/NL AD skin to develop a genomic disease phenotype.
Ewald, David Adrian+8 more
core +2 more sources
Rapid and Sustained Effect of Dupilumab on Work Productivity in Patients with Difficult-to-treat Atopic Dermatitis:Results from the Dutch BioDay Registry [PDF]
Dupilumab treatment improves signs, symptoms, and quality of life in patients with moderate-to-severe atopic dermatitis. This study evaluated the impact of dupilumab treatment on absenteeism, presenteeism, and related costs in a large multi-centre cohort
Ariëns, Lieneke F M+9 more
core +1 more source
Atopic eczema is an itchy inflammatory skin disease with a chronic relapsing–remitting course; it has increased in prevalence in recent decades and now affects up to 25% of school-aged children in the developed world and up to 10% of adults.
Deckert+7 more
core +2 more sources
Successful treatment of trichothiodystrophy with dupilumab
Click here for the corresponding questions to this CME article.
R. Gruber+3 more
openaire +3 more sources
Feasibility Analysis of Interleukin-13 as a Target for a Therapeutic Vaccine [PDF]
Background: The development of therapeutic vaccines requires thorough knowledge of potential hazards associated with long-term inactivation of self-proteins.
Foerster, John, Molęda, Aleksandra
core +2 more sources
Successful use of dupilumab for egg-induced eosinophilic gastroenteritis with duodenal ulcer: a pediatric case report and review of literature [PDF]
Background Non-esophageal eosinophilic gastrointestinal disorder (non-EoE-EGID) is a rare disease in which eosinophils infiltrate parts of the gastrointestinal tract other than the esophagus; however, the number of patients with non-EoE-EGID has been ...
Ikeda, Masanori+8 more
core +1 more source
Dupilumab for the treatment of severe photodermatitis [PDF]
Author(s): Smith, Mary Patricia; Ly, Karen; Thibodeaux, Quinn; Beck, Kristen; Berger, Timothy; Khodosh, Rita; Liao, Wilson; Bhutani ...
Smith, Mary Patricia+7 more
openaire +4 more sources
Topical treatment of dupilumab-associated refractory conjunctivitis and keratitis [PDF]
Purpose: To report 3 cases of severe dupilumab-related conjunctivitis and keratitis topical treatment. Observation: Description, management, and outcomes of dupilumab-related refractory conjunctivitis associated with punctate keratitis.Three patients ...
Ciancaglini, Marco+5 more
core +1 more source
This study identified risk factors for the development of dupilumab-associated ocular surface disease in patients with moderate-to-severe atopic dermatitis in a large prospective daily practice cohort.
Roselie E. Achten+14 more
doaj +1 more source
Neutrophils promote CXCR3-dependent itch in the development of atopic dermatitis. [PDF]
Chronic itch remains a highly prevalent disorder with limited treatment options. Most chronic itch diseases are thought to be driven by both the nervous and immune systems, but the fundamental molecular and cellular interactions that trigger the ...
Barton, Gregory M+11 more
core +1 more source