Results 151 to 160 of about 14,376 (241)

miRScore: A rapid and precise microRNA validation tool. [PDF]

PLoS Comput Biol
Vanek A, Griffiths-Jones S, Meyers BC, Shahid S, Axtell MJ.   +4 more
europepmc   +1 more source

Duplex Ultrasound Surveillance After Endovascular Therapy for Peripheral Artery Disease: An Australian and New Zealand Study

ANZ Journal of Surgery, EarlyView.
ABSTRACT Objective Current practice guidelines lack consensus on optimal surveillance strategies following endovascular interventions for peripheral artery disease (PAD). This study evaluated surveillance practices among vascular surgeons in Australia and New Zealand (ANZ), focusing on duplex ultrasound (DUS) use and factors influencing surveillance ...
Thomas M. Warburton, Shannon D. Thomas, Manar Khashram, Peter Subramaniam, Fernando Picazo‐Pineda, Simon Joseph, Andrew F. Lennox, Nedal Katib, Ramon L. Varcoe   +8 more
wiley   +1 more source

In Silico Development of a Targeted Small Interfering RNA (siRNA) Sequence to Silence Goblet Cell Mucin-5AC Overexpression in Cystic Fibrosis. [PDF]

Cureus
Ahluwalia J, Katakam A, Revuri N, Satish S.   +3 more
europepmc   +1 more source

Real‐time fluorometric isothermal assays for detection of Streptococcus equi subspecies equi and Streptococcus equi subspecies zooepidemicus in horses: Validation, comparison and evaluation of their clinical application

Australian Veterinary Journal, EarlyView.
Infectious diseases significantly impact equine health and welfare, causing illness and death, and loss of productivity globally. One such disease is ‘strangles’, a highly contagious upper respiratory condition in horses caused by Streptococcus equi subspecies equi (SEE).
M Jelocnik, C Hall, S Dennis, K Mitchell, A Blishen, N Mashkour, SI Anstey, C Jenkins, K Jeffers, C El‐Hage, D McMillan, J Gilkerson   +11 more
wiley   +1 more source

An LNA gapmer antisense oligonucleotide inhibitor of human NNMT. [PDF]

Mol Ther Nucleic Acids
Chen S, Poudel BH, Veedu RN.
europepmc   +1 more source

A highly abundant circular RNA from the RMST locus plays a role in posterior fossa ependymoma pathogenesis

Brain Pathology, EarlyView.
circRMST (hsa_circ_0099634) is by far the most abundant isoform from the RMST locus. It is highly expressed in cancer cells throughout ependymoma patient samples and is located in the cytoplasm. circRMST knockdown causes cell cycle arrest and induces differentiation, and it is a marker for poor prognosis. The figure is made using BioRender.
Ulvi Ahmadov, Charlotte W. Udengaard, Stine M. Vissing, Silke D. Nielsen, Kim‐Gwendolyn Dietrich, Benedicte Parm Ulhøi, Lasse S. Kristensen   +6 more
wiley   +1 more source

Direct trapping of the transport-segment DNA by the central domain of type IIA topoisomerases. [PDF]

Sci Adv
Xin Y, Xian R, Liu C, Zhang O, Rao Z, Li X, Chen Y.   +6 more
europepmc   +1 more source

A Conceptual Framework and Methods for Studying the Connectivity of Fishes

Fish and Fisheries, EarlyView.
ABSTRACT Connectivity is a multifaceted concept that has important implications for the management and conservation of marine and freshwater fishes. We developed a conceptual framework that encompasses multiple, interrelated categories of connectedness, including landscape (e.g., structural, functional) connectivity and ecological (e.g., trophic ...
Jordanna N. Bergman, Jessica A. Robichaud, Jasper McCutcheon, Michael T. Booth, Brendan Campbell, Grace A. Casselberry, Cienna R. Cooper, Bronwyn M. Gillanders, Lucas P. Griffin, Edward Hale, Luc LaRochelle, Karen J. Murchie, Mary Peacock, Reid G. Swanson, Simon D. Stewart, Ryan. J. Woodland, Daniel P. Zielinski, Steven J. Cooke, Morgan L. Piczak   +18 more
wiley   +1 more source

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

The FEBS Journal, EarlyView.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

Mechanism for the substrate recognition by a eukaryotic DNA N⁶-adenine methyltransferase complex. [PDF]

Nat Commun
Xu Q, Xie Y, Shi Z.
europepmc   +1 more source