Results 81 to 90 of about 566,348 (288)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Fingerprint-Based Near-Duplicate Document Detection with Applications to SNS Spam Detection

open access: yesInternational Journal of Distributed Sensor Networks, 2014
Social networking has been used widely by millions of people over the world. It has become the most popular way for people who want to connect and interact online with their friends.
Phuc-Tran Ho, Sung-Ryul Kim
doaj   +1 more source

Best-first heuristic search for multicore machines [PDF]

open access: yes, 2010
To harness modern multicore processors, it is imperative to develop parallel versions of fundamental algorithms. In this paper, we compare different approaches to parallel best-first search in a shared-memory setting.
Burns, Ethan   +3 more
core   +1 more source

An objective based classification of aggregation techniques for wireless sensor networks

open access: yes, 2012
Wireless Sensor Networks have gained immense popularity in recent years due to their ever increasing capabilities and wide range of critical applications.
B. Krishnamachari   +22 more
core   +1 more source

Duplicate Defect Detection

open access: yes, 2019
Duplicate Defect Detection Tomi Prifti Discovering and fixing faults is an unavoidable process in Software Engineering. It is always a good practice to document and organize fault reports. This facilitates the effectiveness of development and maintenance process.
openaire   +2 more sources

Object Duplicate Detection

open access: yes, 2011
With the technological evolution of digital acquisition and storage technologies, millions of images and video sequences are captured every day and shared in online services. One way of exploring this huge volume of images and videos is through searching a particular object depicted in images or videos by making use of object duplicate detection ...
openaire   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Quality Assessment of Linked Datasets using Probabilistic Approximation

open access: yes, 2015
With the increasing application of Linked Open Data, assessing the quality of datasets by computing quality metrics becomes an issue of crucial importance. For large and evolving datasets, an exact, deterministic computation of the quality metrics is too
A Hogan   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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