Results 231 to 240 of about 708,679 (282)

Application of microdeletion and microduplication screening in preimplantation genetic testing: a case report. [PDF]

J Med Case Rep
Katz M, Podgursky B, Li S, Zhang Q, Shapiro D, Pasternak M, Siddiqui N, Suer F, Xia Y.   +8 more
europepmc   +1 more source

Aberrant SUMOylation Restricts the Targetable Cancer Immunopeptidome

Advanced Science, EarlyView.
Pharmacological SUMOylation inhibition (SUMOi) counteracts tumor immune evasion by unmasking an immunogenic HLA‐I peptide and neoepitope repertoire. By restoring HLA‐I ligand availability through increased antigen processing and presentation, enhanced proteasomal cleavage, and modulated TAP1 peptide affinity, SUMOi boosts tumor immunogenicity ...
Uta M. Demel, Anna Meurer, Badeel Kh. Q. Zaghla, Bilge Atay, Daniel Steiert, Luca V. Hummel, Konstandina Isaakidis, Chuanbing Zang, Michael Korenkov, Marlon Schielin, Schayan Yousefian, Shima Mecklenbräuker, Marieluise Kirchner, Simon Haas, Antonia Busse, Philipp Mertins, Stefan Müller, Matthias Wirth, Martin G. Klatt, Ulrich Keller   +19 more
wiley   +1 more source

Chromosomal microarray analysis for the prenatal diagnosis in fetuses with fetal echogenic bowel: a retrospective cohort study. [PDF]

BMC Pregnancy Childbirth
Wu W, Tian M, Liu M, Man D, Wang F.
europepmc   +1 more source

Versatile CRISPR‐Cas Tools for Gene Regulation in Zebrafish via an Enhanced Q Binary System

Advanced Science, EarlyView.
This study introduces CRISPR‐Q, a transgenic CRISPR‐Cas system leveraging the QFvpr/QUAS binary expression platform in zebrafish. CRISPR‐Q overcomes previous challenges in achieving stable and efficient gene regulation. By enabling precise spatiotemporal control of transcript knockdown (CRISPR‐QKD) and gene activation (CRISPR‐Qa), it provides a ...
Miaoyuan Shi, Weiqi Ge, Changheng Li, Bin Liu, Xiaoyi Deng, Chengjie Liu, Meijun Zheng, Pu Zhang, Lei Li, Ying Guo, Yunqi Han, Yu Yang, Yanxun V. Yu, Youngnam N. Jin   +13 more
wiley   +1 more source

Case Report: Expanding the diagnostic spectrum of non-invasive prenatal testing to structural chromosomal abnormalities. [PDF]

Front Genet
Kim JC, Kim H, Jang H, Go M, Park JE, Ryu CS, Chin MU, Kim EH, Lee YJ, Shim SH, Cha DH.   +10 more
europepmc   +1 more source

Ruptured Aneurysm in Complete Duplication of the Posterior Cerebral Artery: Successful Treatment With Endovascular Coiling. [PDF]

Cureus
Wu IC, Ko CC, Wu TC, Tsui YK.
europepmc   +1 more source

A de Novo 2q23.1-2q23.3 duplication in a neonate with anemia, thrombocytopenia, and hypospadias: clinical and genomic characterization. [PDF]

Mol Cytogenet
Zhang B, Zhang C, Chen P, Hao R, An L.
europepmc   +1 more source

Case Report: A rare case of myopic macular pit mimicking duplication of the optic disc. [PDF]

Front Med (Lausanne)
Zhou S, Hu M, Sun Y, Wang Z, Luo T.
europepmc   +1 more source

Correction: Reticulate evolutionary history underpins a revised generic circumscription of Paphiopedilum (Orchidaceae): insights from integrative phylogenomics and historical biogeography. [PDF]

BMC Plant Biol
Górniak M, Olędrzyńska N, Szlachetko DL.   +2 more
europepmc   +1 more source