Results 111 to 120 of about 100,798 (267)

Meflin/ISLR is a meningeal cell‐specific marker involved in the development of meninges and meningioma progression

Brain Pathology, EarlyView.
Mesenchymal stromal cell‐and fibroblast‐expressing Linx paralogue (Meflin) is expressed in embryonic meninges and contributes to meningeal homeostasis. In meningiomas, elevated Meflin correlates with higher grade and recurrence. Single‐cell RNA sequencing revealed a Meflin‐high tumor cell subset marked by reduced proliferation, WNT6 expression, and ...
Yukihiro Shiraki, Tomotsugu Kurauchi, Akitoshi Hara, Nobutoshi Esaki, Shinji Mii, Ryota Ando, Akihiro Sakai, Kuniaki Tanahashi, Fumiharu Ohka, Ryuta Saito, Atsushi Natsume, Yuki Hattori, Takaki Miyata, Atsushi Enomoto   +13 more
wiley   +1 more source

Activation of peripheral NOP receptors reduces periorbital mechanical allodynia evoked by CGRP in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Migraine is a neurovascular disorder largely mediated by calcitonin gene‐related peptide (CGRP). This study explores the role of the nociceptin/orphanin FQ (N/OFQ)–N/OFQ receptor (NOP) system in CGRP‐induced periorbital mechanical allodynia (PMA) in mice.
Chiara Sturaro, Pietro Pola, Michela Argentieri, Alessia Frezza, Matilde Marini, Francesco De Logu, Valentina Albanese, Marie Soukupova, Davide Malfacini, Nurulain T. Zaveri, Romina Nassini, Dane D. Jensen, Pierangelo Geppetti, Girolamo Calò, Chiara Ruzza   +14 more
wiley   +1 more source

Systematic review and meta-analysis of the biomechanical properties of the human dura mater applicable in computational human head models [PDF]

, 2022
Quinton Pearcy, Joanna Tomlinson, Justyna A. Niestrawska, Dustin Möbius, Ming Zhang, Johann Zwirner   +5 more
openalex   +1 more source

Discrimination between spinal extradural meningioma and both intra and extradural meningioma : Case Report [PDF]

, 2017
2017-02Meningiomas are common spinal tumor and mostly located at intradura. Recurrence rate after surgery for extradural meningioma was higher than intradural meningioma. A patient with intra and extradural spinal meningioma was treated and discussed its
69557, 69558, 69559, 69560, 69561, 69562, 69563, 69564, 69565, 69566, 69567, Ando, Kei, Hida, Tetsuro, Imagama, Shiro, Ishiguro, Naoki, Ito, Kenyu, Kobayashi, Kazuyoshi, Matsumoto, Akiyuki, Morozumi, Masayoshi, Nishida, Yoshihiro, Tanaka, Satoshi, Tsushima, Mikito   +21 more
core  

Matsupexole: A novel nonergot dopamine receptor agonist with sustained efficacy in a rat model of Parkinson's disease and limited off‐target activity

British Journal of Pharmacology, EarlyView.
Background and Purpose Dopamine receptor agonists, particularly targeting the dopamine D2L receptor (D2LR), have been used to treat Parkinson's disease (PD). However, valvular heart disease and somnolence, mainly caused by activating the serotonin 5‐HT2B receptor (5‐HT2BR) and dopamine D3 receptor (D3R), respectively, currently challenge their clinical
Takayuki Suzuki, Fumiki Oana, Masaki Oota, Yuma Handa, Osamu Kaminuma   +4 more
wiley   +1 more source

Dynamic Active Constraints for Surgical Robots using Vector Field Inequalities

, 2019
Robotic assistance allows surgeons to perform dexterous and tremor-free procedures, but robotic aid is still underrepresented in procedures with constrained workspaces, such as deep brain neurosurgery and endonasal surgery.
Adorno, Bruno V., Harada, Kanako, Marinho, Murilo M., Mitsuishi, Mamoru   +3 more
core   +1 more source

The Bonebridge Active Bone Conduction Hearing Implant: Safety, Effectiveness and Outcomes Based on 355 Patients

Clinical Otolaryngology, EarlyView.
ABSTRACT Objectives This study evaluates the safety and efficacy of the Bonebridge BCI 601 and 602 bone conduction implants in our largest cohort to date of 355 patients. The patients had a wide age range and exhibited conductive, mixed, or single‐sided deafness (SSD). Design All patients underwent Bonebridge implantation.
Piotr Henryk Skarzynski, Katarzyna Beata Cywka, Emilia Anna Czaplicka, Henryk Skarzynski   +3 more
wiley   +1 more source

Acute neurologic presentation of a 2‐year‐old standardbred colt with multicentric diffuse large B cell lymphoma

Equine Veterinary Education, EarlyView.
Summary Lymphoma in horses is uncommon and rarely diagnosed as a cause of ataxia. This case report describes a 2‐year‐old Standardbred cryptorchid colt who presented with acute onset of grade 3–4/5 spinal ataxia in all four limbs, with the hindlimbs more severely affected than forelimbs and severe proprioceptive deficits.
K. MacMillan, J. Burns, E. John, M. Buote   +3 more
wiley   +1 more source

Risk factors associated with owner‐reported sleep disturbances in Nordic horses

Equine Veterinary Journal, EarlyView.
Abstract Background Very little is known about sleep disturbances in horses, although several management or animal‐based factors may contribute to an increased risk of disturbances. Objectives To investigate factors related to rest and sleep behaviour of horses kept in stalls as perceived by Nordic horse owners or caretakers and their association with ...
H. Suomala, I. Brotherus, L. Hänninen, E. Ternman, A. K. Mykkänen   +4 more
wiley   +1 more source

Retrospective review of spinal magnetic resonance images to determine the margin of safety for epidural analgesia in pediatric patients

Brazilian Journal of Anesthesiology
Background: Deeply sedated children cannot provide feedback if an epidural needle traumatizes the Spinal Cord (SC). Knowing relevant structure depths may, therefore, improve safety.
Noah Letofsky, Dana Archibald, Anthony M.-H. Ho, Lais Helena N. e Lima, Rodrigo M. e Lima, Vinicius C. Quintão, Fernando B. Cançado, Ricardo V. Carlos, Leopoldo M. da Silva, Fernando N. Bellicieri, Saullo Q. Silveira, Arvin Haghighat, Rachel Phelan, Glenio B. Mizubuti   +13 more
doaj   +1 more source