Results 91 to 100 of about 35,503 (207)

High‐altitude headache: Insights into pathophysiology and potential treatment implications

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude headache occurs during prolonged exposure to low oxygen, such as during ascent to high altitude. Several risk factors increase its likelihood, with the degree of hypoxia, often driven by rapid ascent to greater altitudes, being the most prominent factor.
Marika Falla, Florian Frank, Giacomo Strapazzon, Justin Lawley   +3 more
wiley   +1 more source

In Vivo Electrochemical Monitoring of Safinamide Pharmacokinetics in the Brain Explores Its Correlation With Vision‐Related Neuronal Activity

Advanced Science, Volume 13, Issue 43, 3 August 2026.
An electrochemical platform based on differential pulse amperometry enables real‐time, selective tracking of safinamide pharmacokinetics in the living brain with high spatiotemporal resolution. When integrated with electrophysiology, this approach reveals that drug‐induced suppression of vision‐related neuronal activity provides mechanistic insight ...
Xiaoke Nan, Chuqi Li, Qianhe Dai, Junlan Zhou, Lijiao Cao, Yuying Liu, Jinger Chen, Meiping Xiong, Yuhang Jiang, Xianchan Li   +9 more
wiley   +1 more source

Retrospective review of spinal magnetic resonance images to determine the margin of safety for epidural analgesia in pediatric patients

Brazilian Journal of Anesthesiology
Background: Deeply sedated children cannot provide feedback if an epidural needle traumatizes the Spinal Cord (SC). Knowing relevant structure depths may, therefore, improve safety.
Noah Letofsky, Dana Archibald, Anthony M.-H. Ho, Lais Helena N. e Lima, Rodrigo M. e Lima, Vinicius C. Quintão, Fernando B. Cançado, Ricardo V. Carlos, Leopoldo M. da Silva, Fernando N. Bellicieri, Saullo Q. Silveira, Arvin Haghighat, Rachel Phelan, Glenio B. Mizubuti   +13 more
doaj   +1 more source

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

Advanced Science, Volume 13, Issue 43, 3 August 2026.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong, Dong Sun, Hao‐Han Guo, Daehoon Lee, Zhipeng Liu, Lin Mei, Wen‐Cheng Xiong   +6 more
wiley   +1 more source

Evaluation of IHH, PTCH1, and SMO protein immunohistochemistry in the human mandibular condyle at fetal stages from 30 to 80 mm greatest length

The Anatomical Record, Volume 309, Issue 8, Page 2176-2188, August 2026.
Abstract This study evaluated the morphogenesis of the temporomandibular joint (TMJ) in human fetuses during the third month of gestation through the analysis of immunohistochemistry for the proteins Indian Hedgehog (IHH), Patched‐1 (PTCH1), and Smoothened (SMO).
Filipe Santos da Silva, Carolina de Oliveira Gigek, Andreia Fabiana Do Vale Franco, Amanda Alves Ribeiro Massoni, José Ramon Mérida‐Velasco, Luís Otávio Carvalho de Moraes   +5 more
wiley   +1 more source

Case Report: Dural infiltration of intervertebral disc material mimicking spinal cord meningioma in a dog

Frontiers in Veterinary Science
A six-year-old mixed-breed dog presented with a two-month history of peracute back pain and right hindlimb monoparesis. Neurological examination revealed reduced proprioceptive positioning of the right hindlimb, and palpation of the L2–L4 area elicited a
Karin Sakamoto, Yukiko Nakano, James K. Chambers, Yui Kobatake, Yui Kobatake, Yui Kobatake, Masao Mizuno, Hiroaki Kamishina   +7 more
doaj   +1 more source

Nucleus Pulposus Resorption Following a Paraspinal Hook‐Needle Intervention for Lumbar Disc Herniation: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT The paraspinal hook‐needle intervention is a minimally invasive needle‐based procedure performed under local anesthesia using a specialized hook‐shaped needle at clinically selected lumbar segments. We report the case of a 70‐year‐old woman who presented with intermittent low back pain for more than 10 years, recently aggravated and ...
Mengying Xiao, Zhengchao Cai, Hairui Zhu, Shuanglin Mou, Wensheng Zhu   +4 more
wiley   +1 more source

Multidisciplinary Approach in Management of Currarino Syndrome in a Female Infant: A Case Report on Rare Congenital Triad and Focused Literature Review

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Currarino Syndrome (CS) should be suspected in infants presenting with persistent constipation and sacral anomalies. Early diagnosis using appropriate imaging and multidisciplinary surgical management is essential to prevent serious complications such as bowel obstruction, infection, and neurological impairment.
Ferdinand Medard Shilikale, Cui Mingyu, Liu Guihai, Rajabu Athumani Bakari, Jiao Chenwei   +4 more
wiley   +1 more source

Surgical Treatment of Lateral Skull Base Tumors Extending to the Craniovertebral Junction

Head &Neck, Volume 48, Issue 8, Page 2271-2280, August 2026.
ABSTRACT Objective To evaluate the clinical manifestation, surgical strategies, and long‐term outcomes of lateral skull base tumors extending to the craniovertebral junction (CVJ), with a focus on the infratemporal fossa approach (IFA) and individualized treatment options for cervical‐occipital stability.
Songbo Xue, Yang Zhao, Huiying Sun, Hanlin Chen, Yong Zhao, Xin Ding, Wanru Zheng, Fei Ren, Yiwei Zhao, Jiajing Tong, Yu Chen, Zhiqiang Gao, Xu Tian, Siyi Cai, Guodong Feng   +14 more
wiley   +1 more source

PERIOSTEAL DISEASE AFFECTING THE DURA MATER. [PDF]

The Lancet
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openaire   +2 more sources