Results 111 to 120 of about 99,540 (256)

Dual pharmacological targeting of coactivator‐associated arginine methyltransferase 1 (CARM1) and salt inducible kinase (SIK) drives ketogenesis in both hepatocytes and mice

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Ketone bodies are liver‐derived circulating energy metabolites that positively impact most hallmarks of ageing. Ketone bodies increase during calorie restriction and fasting, two of the more widely perceived methods to increase health span.
Tábata Bergonci, Troels Kjær Rosenbæk, Samuel J. Windross, Ulrik B. Keiding, Estéfano Pinilla, Katrine P. Stuckert, Jakob Hansen, Camilla B. Nielsen, Jemila Peter Gomes, Lucy R. Davies, Johan Palmfeldt, Volker Loeschcke, Charlotte U. Andersen, Ulf Simonsen, Thomas B. Poulsen, Mogens Johannsen   +15 more
wiley   +1 more source

Capsaicin-szenzitív neurogén mechanizmusok a meningeális nocicepcióban és a dura mater vaszkuláris reakcióinak modulációjában = Role of capsaicin-sensitive neurogenic mechanisms in meningeal nociception and in the modulation of vascular reactions of the dura mater [PDF]

, 2010
Kísérleteink során morfológiai és funkcionális módszerekkel igazoltuk a trigemino-vaszkuláris capsaicin szenzitív CGRP-immunreaktív nociceptív afferens idegek jelenlétét patkány kemény agyhártyájában.
Dux, Mária, Jancsó, Gábor, Somodiné Boros, Krisztina, Sántha, Péter, Tóth, Dorina   +4 more
core  

Cone beam computed tomographic myelography in horses with cervical vertebral compressive myelopathy

Equine Veterinary Journal, EarlyView.
Abstract Background While computed tomographic (CT) myelography is increasingly available and has been evaluated in alive horses, objective criteria for diagnosing cervical vertebral compressive myelopathy (CVCM) are lacking. Objectives To establish morphometric dimensions of the cervical vertebral canal and spinal cords from horses with CVCM and ...
Sonia González‐Medina, Myra F. Barrett, Tawfik A. Aboellail, Bradley B. Nelson, Yvette S. Nout‐Lomas   +4 more
wiley   +1 more source

Mechanical properties of cervical dura mater.

Acta of bioengineering and biomechanics, 2012
The aim of the study was to determine experimentally the stress as strain function as well as the orthotropy and heterogeneity of porcine dura mater of the cervical spinal cord. Material was divided into groups based on the place of collection, considering the dorsal side and ventral side, specifying the number of cervical vertebra, and the direction ...
Mazgajczyk, Emilia, Ścigała, Krzysztof, Czyż, Marcin, Jarmundowicz, Włodzimierz, Będziński, Romuald   +4 more
openaire   +1 more source

Anatomy of spinal CSF loss in the American alligator (Alligator mississippiensis)

Journal of Anatomy, Volume 246, Issue 4, Page 575-584, April 2025.
India ink introduced into the cranial cerebrospinal fluid (CSF) compartment of Alligator diffuses along the spinal cord and exits the spinal compartment using perineural flow, resulting in a prominent “ink cuff” forming at the base of the spinal nerve. In Alligator, the region of the ink cuff is drained by a small lymphatic vessel.
Hadyn DeLeeuw, Michael Cramberg, Matthew Dille, Emily Pick, Mary Thompson, Bruce A. Young   +5 more
wiley   +1 more source

Virtual brain endocasts of the palaeanodont Metacheiromys marshi and the neurosensory evolution of early Pholidotamorpha

Journal of Anatomy, EarlyView.
We describe the endocranial anatomy of Metacheiromys marshi. Decrease in olfaction and eye movement control occurred through time in Pholidotamorpha and is likely linked to fossorial adaptations. The development of the orbital gyrus might be related to the evolution of myrmecophagy and the emergence of a protrusile tongue in early Pholidotamorpha ...
Eduard Cabasés Bru, Raquel Moya‐Costa, John R. Wible, Stephen L. Brusatte, Ornella C. Bertrand   +4 more
wiley   +1 more source

Ageing‐related modification of sleep and breathing in orexin‐knockout narcoleptic mice

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Narcolepsy type‐1 (NT1) is a lifelong sleep disease, characterised by impairment of the orexinergic system, with a typical onset during adolescence and young adulthood. Since the wake–sleep cycle physiologically changes with ageing, this study aims to compare sleep patterns between orexin‐knockout (KO) and wild type (WT) control mice at ...
Stefano Bastianini, Sara Alvente, Chiara Berteotti, Viviana Lo Martire, Gabriele Matteoli, Elena Miglioranza, Alessandro Silvani, Giovanna Zoccoli   +7 more
wiley   +1 more source

Characterisation of sleep apneas and respiratory circuitry in mice lacking CDKL5

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary CDKL5 deficiency disorder is a rare genetic disease caused by mutations in the CDKL5 gene. Central apneas during wakefulness have been reported in patients with CDKL5 deficiency disorder. Studies on CDKL5‐knockout mice, a CDKL5 deficiency disorder model, reported sleep apneas, but it is still unclear whether these events are central (central ...
Gabriele Matteoli, Sara Alvente, Stefano Bastianini, Chiara Berteotti, Elisabetta Ciani, Elenia Cinelli, Viviana Lo Martire, Giorgio Medici, Tommaso Mello, Elena Miglioranza, Alessandro Silvani, Donatella Mutolo, Giovanna Zoccoli   +12 more
wiley   +1 more source

Retrospective review of spinal magnetic resonance images to determine the margin of safety for epidural analgesia in pediatric patients

Brazilian Journal of Anesthesiology
Background: Deeply sedated children cannot provide feedback if an epidural needle traumatizes the Spinal Cord (SC). Knowing relevant structure depths may, therefore, improve safety.
Noah Letofsky, Dana Archibald, Anthony M.-H. Ho, Lais Helena N. e Lima, Rodrigo M. e Lima, Vinicius C. Quintão, Fernando B. Cançado, Ricardo V. Carlos, Leopoldo M. da Silva, Fernando N. Bellicieri, Saullo Q. Silveira, Arvin Haghighat, Rachel Phelan, Glenio B. Mizubuti   +13 more
doaj   +1 more source

Induction powered biological radiosonde [PDF]

, 1980
An induction powered implanted monitor for epidurally measuring intracranial pressure and telemetering the pressure information to a remote readout is disclosed.
Fryer, T. B.
core   +1 more source