Results 41 to 50 of about 193,384 (263)

Dynamic Mechanical Properties and Microstructure of Graphene Oxide Nanosheets Reinforced Cement Composites

open access: yesNanomaterials, 2017
This paper presents an experimental investigation on the effect of uniformly dispersed graphene oxide (GO) nanosheets on dynamic mechanical properties of cement based composites prepared with recycled fine aggregate (RFA).
Wu-Jian Long   +3 more
doaj   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha   +4 more
wiley   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Characterization of coal reservoir permeability evolution under thermo-mechanical coupling based on fractal theory

open access: yesScientific Reports
One important factor influencing the gas/water two-phase seepage during coalbed methane extraction is the absolute permeability of coal reservoirs.
Kaide Liu   +5 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Vibration Reduction on Circular Disks with Vibroacoustic Metamaterials

open access: yesApplied Sciences
Vibroacoustic metamaterials represent an innovative technology developed for broadband vibration reduction. They consist of an array of local resonators and are able to reduce vibrations over a wide frequency range, commonly referred to as a stop band ...
Sebastian Rieß   +4 more
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

Mechanical properties of aeolian sand cemented via microbially induced calcite precipitation (MICP)

open access: yesScientific Reports
The cementation of desert aeolian sand is a key method to control land desertification and dust storms, so an economical, green and durable process to reach the binding between sand grains needs to be searched. The method based on the microbially induced
Gang Li   +4 more
doaj   +1 more source

Connotation and Model Analysis of Rail Transit Interconnection and Interoperability under Multi-Network Integration Background

open access: yesChengshi guidao jiaotong yanjiu
[Objective] At present, the regional rail transit system in China has entered a new stage of multi-network integrated development, and its operation and management also presents new characteristics of multi-level, multi-dimensional collaborative ...
LIU Yuxing   +4 more
doaj   +1 more source

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