Results 151 to 160 of about 2,222,232 (296)

Quantifying Visuomotor Maturation From Middle Childhood to Adolescence. [PDF]

Dev Psychobiol
Niechwiej-Szwedo E, Christian LW.
europepmc   +1 more source

Durational Feminisms: Collectivity, Support and Intergenerational Exchange

Helena Reckitt discusses how the Feminist Duration Reading Group, which she initiated in 2015, attempts to bring feminist texts, movements and ideas from previous eras into dialogue with current urgencies. She explains the group’s process, which includes incorporating practices of entrustment drawn from Italian feminism, and of reading out loud ...
openaire  

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Acute brain dysfunction clusters in COVID-19: a pilot machine learning-based analysis of the COVID-D cohort. [PDF]

Intensive Care Med Exp
Romero-García N, Montosa-I-Micó V, Fernández-Narro D, García-Gómez JM, Hurtado L, Passariello E, Taccone FS, Robba C, Raman R, Orun OM, Pandharipande P, Pun BT, Ely EW, Badenes R, Sáez C.   +14 more
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Application of Digital Health Technologies in Cardiac Rehabilitation for Patients With Coronary Heart Disease: Scoping Review. [PDF]

J Med Internet Res
Zhu X, Liu L, Wang Y, Li H, Zang M, Wang J, Tian Y, Li Z.   +7 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Diagnostic turnaround time and antimicrobial use in suspected central nervous system infection: a regional Australian cohort study. [PDF]

Antimicrob Steward Healthc Epidemiol
Galimam SS, Randall H, Heard S, Oze V, Robertson M.   +4 more
europepmc   +1 more source

856-1 Mechanical circulatory support: Evolving trends in support duration

Journal of the American College of Cardiology, 2004
openaire   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source