Results 131 to 140 of about 2,222,232 (296)

Early Detection and Prevention of Mental Health Problems: Developmental Epidemiology and Systems of Support

Journal of Clinical Child & Adolescent Psychology, 2016
E. Costello
semanticscholar   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Parental play beliefs as a factor in the frequency of preschoolers' requests for parent-child play and its duration. [PDF]

Front Psychol
Gavrilova M, Dvorskaya E.
europepmc   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Incidence and clinical outcomes of extended duration support in patients with Impella 5.5 - Analysis from the LOQI Registry. [PDF]

JHLT Open
Kaczorowski D, Nguyen VP, Afzal A, Silvestry SC, Zeeshan A, Yanamala N, Matthews R, Chhim R, Aggarwal S, Somo SI, Hickey GW.   +10 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Modified Tal (M-Tal) Score as a Predictor of Outcomes in Infants with Bronchiolitis: A Prospective Study. [PDF]

Pediatr Rep
Magh I, Das RR, Mohapatra R, Panda S, Mohakud NK.   +4 more
europepmc   +1 more source

Post-cardiac transplant survival after support with a continuous-flow left ventricular assist device: impact of duration of left ventricular assist device support and other variables.

Journal of Thoracic and Cardiovascular Surgery, 2010
R. John, F. Pagani, Y. Naka, A. Boyle, J. Conte, S. Russell, C. Klodell, C. Milano, J. Rogers, D. Farrar, O. Frazier   +10 more
semanticscholar   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Which spatiotemporal parameters are predicted by commonly used osteoarthritis questionnaires in clinical practice? An exploratory study. [PDF]

BMC Musculoskelet Disord
Deniz G, Esmez O, Alkan G, Bilek F.
europepmc   +1 more source