Phase III, randomized, open-label study of durvalumab (MEDI4736) monotherapy, or durvalumab + tremelimumab, versus standard of care (SoC), in recurrent or metastatic (R/M) squamous cell carcinoma of the head and neck (SCCHN): eagle [PDF]
core +1 more source
Agnostic phase II, multicenter, single-arm study with DURVAlumab plus carboplatin or cisplatin and etoposide as first-line treatment in extensive stage - Extrapulmonary Small Cell Carcinoma (EPSCC) patients - DURVASCC trial (GOIRC-01-2021). [PDF]
Damato A +18 more
europepmc +1 more source
Emerging Therapeutic Synergies: Combining PD-1 Inhibitors With Poly-ADP-Ribose Polymerase (PARP) Inhibitors in the Treatment of Gynecologic Cancers. [PDF]
Mohamed Azhar MS +6 more
europepmc +1 more source
Comparative efficacy and safety of targeted therapeutics or immunotherapy agents combined with chemotherapy as first-line treatment for advanced biliary tract cancer: a systematic review and network meta-analysis. [PDF]
Ma H, Wang Z, Tong Y, Li H, Han Y, He D.
europepmc +1 more source
Expression of carcinoma ecotypes in the tumor microenvironment predicts response to neoadjuvant therapy in early-stage breast cancer. [PDF]
Asleh K, Bethune G, Marcato P.
europepmc +1 more source
Precision targeted-immunotherapy for BRAF V600E and MET-amplified biliary tract cancer: two case reports. [PDF]
He X +5 more
europepmc +1 more source
Impact of LEAP-012 and EMERALD-1 in the management of HCC. [PDF]
Singal AG +3 more
europepmc +1 more source
Rationale and design for a phase IIIb trial of first-line tremelimumab plus durvalumab versus pembrolizumab, in combination with chemotherapy, in patients with non-squamous metastatic non-small-cell lung cancer and mutations or co-mutations in <i>STK11, KEAP1</i>, or <i>KRAS</i>: the TRITON study. [PDF]
Skoulidis F +13 more
europepmc +1 more source
Durvalumab in Advanced Biliary Tract Cancer: Real-World Data From a Large Cohort of Patients Across Multiple International Centers. [PDF]
Rimini M +70 more
europepmc +1 more source
Acute Cerebellitis Due to Administration of Durvalumab for Recurrent Endometrial Cancer: A Case Report. [PDF]
Kawahara H +4 more
europepmc +1 more source

