Results 161 to 170 of about 534,695 (315)

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Spatial heterogeneity of hotspot mutations and clonal relatedness in ovarian endometrioid carcinoma

open access: yesMolecular Oncology, EarlyView.
Spatially resolved analysis revealed heterogeneous distributions of selected cancer‐associated mutations within ovarian endometrioid carcinomas. Shared mutations between paired endometrial and ovarian tumors supported clonal relatedness. These findings highlight the value of sampling multiple tumor regions when interpreting molecular profiles ...
Takahito Ashihara   +10 more
wiley   +1 more source

Government resisted lobbying on betting duty but won't use the funds for problem gambling services.

open access: yes, 2019
An extra €50 million is set to be raised from the betting duty this year, and activists are asking for even 10% of it for problem gambling..... [Please note, the prevalence figures referenced in this article were published by the Department of Health,
Murray, Sean
core  

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Untitled #12 from Tour of Duty, 1999 [picture] /

open access: yes, 2004
Title from inscription.; Published title is: "INTERFET shooting range, Dili, 1999" in Tour of Duty.; Photographer's signature below photograph and on verso lower right.; Also available in an electronic version via the Internet at: http://nla.gov.au/nla ...
Sleeth, Matthew, 1972-
core  

A duty of kindness [PDF]

open access: yesJournal of the Royal Society of Medicine, 2016
openaire   +2 more sources

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Duty-Free Quota-Free Market Access for LDCS: Falling Within or Outside the GSP Downsides?

open access: yes, 2013
The article offers information on the development and implementation of duty-free quota-free (DFQF) market access regime for least developed country (LDC) under the Generalized System of Preference (GSP) mechanism.
Sharmin Tania (7849707)
core  

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