Results 31 to 40 of about 238,417 (269)

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Study on the effect of aquatic exercise combined with hot spring bathing for patients with chronic low back pain: a randomized controlled trial

BMC Sports Science, Medicine and Rehabilitation
Background Chronic low back pain (CLBP) is a common musculoskeletal symptom associated with spinal disorders, impairing quality of life while imposing significant medical and socioeconomic burdens.
Lingli Qin, Nian Dong, Yufei Zhao, Jie Li, Ali Li, Chao Zhou, Xin Nie, Lina Zhang, Hongyu Yu   +8 more
doaj   +1 more source

Ancient Vedic Literature and Human Rights: Resonances and Dissonances

Cogent Social Sciences, 2021
The Vedic literature constitutes the fulcrum of Sanskrit literature and is repositories of some fundamental concepts of human rights. This manuscript endeavors to decode the tenets of human rights concealed in the Vedic texts.
Shailendra Kumar, Sanghamitra Choudhury
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Dynamic Analysis for a Disk-Inertial-Asymmetry Rotor System

Shock and Vibration
In this paper, the dynamic characteristics of a rotor with disk inertial asymmetry are investigated. A rotor model is developed using the Lagrange method, and a modal analysis technique based on Hill’s determinant is derived.
Di Liu, Jie Hong, Yinli Feng
doaj   +1 more source

Nonlinear Analysis of Rod Fastened Rotor under Nonuniform Contact Stiffness

Shock and Vibration, 2020
Rod fastened rotor is widely used in gas turbine, aero engine, and other occasions. The bending stiffness of the contact interface directly affects the stable operation of the rotor.
Jiaqi Li, Yao Li, Fan Zhang, Yinli Feng
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Numerical Investigation on the Flow Characteristics in Axial-Inlet Cover-Plate Cavities

Energies
This paper investigates the complex flow characteristics and parameter prediction methods for axial-inlet cover-plate cavities in pre-swirl systems numerically.
Zengyan Lian, Pei Wang, Guang Liu, Ziyi Sun, Jun Liu, Huiping Pei, Wenying Ju, Xingen Lu   +7 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Research on combined winglet design method and aerothermodynamic loss control for high load variable geometry turbine

Case Studies in Thermal Engineering
As a key component of variable-cycle engines and gas turbines, the variable geometry turbine adjusts the vane setting angle to maintain efficiency under off design conditions.
Mai Li, Jun Liu, Hang Yuan, Wenying Ju, Pei Wang, Zengyan Lian, Xingen Lu   +6 more
doaj   +1 more source