Results 41 to 50 of about 238,417 (269)
Utilitas, 2011 In his recent book, Killing in War, Jeff McMahan sets out a number of conditions for a person to be liable to attack, provided the attack is used to avert an objectively unjust threat: (1) The threat, if realized, will wrongfully harm another; (2) the person is responsible for creating the threat; (3) killing the person is necessary to avert the threat,
openaire +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
The position and authorizations of enforcement officers in the Belarusian legal system
Pravo, 2020 Considering the fact that the profession of the enforcement officer has an increasingly efficient role both in securing and realizing creditors’ claims, which was significantly contributed by the introduction of the system of the enforcement officers as ...
Vujadin Masnikosa
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
STFF-CANet Diagnosis Model of Aero-Engine Surge Based on Spatio-Temporal Feature Fusion
AerospaceAero engine surge diagnosis is a key technology in engine health management, and its diagnostic accuracy is of great significance for ensuring operational safety.
Chunyan Hu +5 more
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The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Moral equality of soldiers in war: Necessity of separating jus ad bellum from jus in bello [PDF]
Војно дело, 2016 In a world and age in which wars are a daily phenomenon, soldiers and combatants are often times judged as moral or immoral based on the morality of the war they are fighting.
Stanar Dragan
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pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
BASIC MORAL STANDARDS IN ETIC SYSTEM OF I. KANT
Дискурс, 2017 The article reviews main items of I. Kant ethical system based on I. Kant work “Critique of Pure Reason”, “Groundwork of the Metaphysics of Morals”, “Prolegomena to Any Future Metaphysics”. The article analyzes the main issues of I. Kant philosophy: will
A. M. Sklyarovа
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