Results 61 to 70 of about 238,417 (269)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Обов'язки подружжя, що виникають з приводу спільної сумісної власності

Проблеми Законності, 2016
У статті досліджуються обов’язки подружжя, що виникають з приводу спільної сумісної власності. Ааналізується питання можливості (неможливості) укладення правочинів одним із подружжя з приводу спільного майна без згоди іншого.
Вікторія Валентинівна Надьон
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Noise Elimination and Reduction Structure for Tram Air-conditioning Return Duct

Chengshi guidao jiaotong yanjiu
Objective The noise generated by air-conditioning system is a primary source of static noise in trams, with most of the interior noise originating from the air-conditioning supply fan.
LI Dengke, LIU Youmei, FAN Yunxin, LIU Xiaobo, WANG Xianfeng, CHEN Shiwen   +5 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Harmonic Frequency Analysis of Asynchronous Motion in a Rubbing Rotor System with Flexible Casing Constraint

Aerospace
Rotor-flexible casing rubbing can induce strong nonlinear dynamics in rotor systems. This study investigates the harmonic frequency characteristics of a rubbing rotor system with a flexible casing constraint.
Di Liu, Xingen Lu, Yinli Feng
doaj   +1 more source

Is there a Duty to Vote?

Social Philosophy and Policy, 2000
The genre of public service advertisements that appear with two- and four-year cyclical regularity is familiar. Cameras pan across scenes of marines hoisting the flag on Iwo Jima, a bald eagle soaring in splendid flight, rows of grave markers at Arlington.
BRENNAN, geoffrey, Lomasky, Loren
openaire   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Blade performance prediction model coupled autoencoder with multi-source data fusion strategy

Engineering Applications of Computational Fluid Mechanics
The use of artificial intelligence to develop data-driven aerodynamic performance prediction models has recently become a research hotspot, as it offers significant advantages in computational speed and cost compared to traditional wind tunnel ...
Ruoyu Chen, Ziliang Li, Huafeng Xu, Qingkuo Li, Mingyang Wang, Xu Dong, Ge Han, Xingen Lu   +7 more
doaj   +1 more source