Results 61 to 70 of about 534,695 (315)
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Social Philosophy and Policy, 2000 The genre of public service advertisements that appear with two- and four-year cyclical regularity is familiar. Cameras pan across scenes of marines hoisting the flag on Iwo Jima, a bald eagle soaring in splendid flight, rows of grave markers at Arlington.
BRENNAN, geoffrey, Lomasky, Loren
openaire +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Lessons of the 1999 Abolition of Intra-EU Duty Free Sales for Eastern European EU Candidates [PDF]
At the end of June 1999 the intra-EU duty free shopping was abolished among the fifteen member nations. The opponents of this resolution argued that such a tax-free sales sector created jobs EU-wide and hardly reduced the value added and excise tax ...
Andrea Gebauer +2 more
core +2 more sources
STFF-CANet Diagnosis Model of Aero-Engine Surge Based on Spatio-Temporal Feature Fusion
AerospaceAero engine surge diagnosis is a key technology in engine health management, and its diagnostic accuracy is of great significance for ensuring operational safety.
Chunyan Hu +5 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Duty of Confidentiality: Myth or Reality? [PDF]
, 2012 Explores the extent to which there is a duty of confidentiality in relation to the information used in arbitration proceedings. Considers how the duty is regulated by arbitration rules in different countries and whether there is a sufficient consensus to
Yu, Hong-Lin
core
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Architect's continuing duty to review design [PDF]
, 2009 Architects are design professionals that are retained for their design expertise and an architect that enters into an agreement with the client has specific duties that he has to perform; he has a duty to exercise reasonable skill and care in carrying ...
Meor Adam, Arfah Hanum
core
BASIC MORAL STANDARDS IN ETIC SYSTEM OF I. KANT
Дискурс, 2017 The article reviews main items of I. Kant ethical system based on I. Kant work “Critique of Pure Reason”, “Groundwork of the Metaphysics of Morals”, “Prolegomena to Any Future Metaphysics”. The article analyzes the main issues of I. Kant philosophy: will
A. M. Sklyarovа
doaj +1 more source