Results 61 to 70 of about 563,853 (302)

Two Lawyers, One Client, and the Duty to Communicate: A Gap in Rules 1.2 and 1.4 [PDF]

open access: yes, 2013
[Excerpt] “There may have been a day in which most American legal matters involved one client and one lawyer, but that day has surely passed. People today travel widely, businesses sell their goods and services across the country, and activity of all ...
Sieberson, Stephen C.
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Reforms in the Holy Infirmary, 1680 [PDF]

open access: yes, 2007
The Holy Infirmary, at least in theory, bore witness to the very raison d'etre of the Order of St John ­ the care of the infirm. If the knights came to be known as the Hospitallers, it is because the care of the sick became their historical mission ...
Bonello, Giovanni
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Trauma Management Therapy and Prolonged Exposure Therapy for PTSD in an active duty sample: Design and methodology of a randomized clinical trial

open access: yesContemporary Clinical Trials Communications, 2020
Posttraumatic stress disorder (PTSD) resulting from military service is a common, yet often chronic condition. Treatment outcome often is attenuated by programs that are (a) lengthy in nature and (b) constricted in their target outcomes.
Deborah C. Beidel   +8 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

El concepto de impunidad a la luz del Derecho internacional: Una aproximación sistémica desde el Derecho internacional penal y el Derecho internacional de los derechos humanos

open access: yesRevista Electrónica de Estudios Internacionales, 2012
Although the concept of impunity in a first approach has been usually translated as the simple absence of punishment or lack of penalty, it is true that this concept involves much more than that; in fact its content is in a permanent state of development
Javier Chinchón Álvarez
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Evaluating the Potential of Decision Tree Modeling to Augment Return-to-Duty Decisions Following Major Limb Injury

open access: yesTechnologies
Advances in medical care now enable significant functional recovery after traumatic limb injuries. The return-to-duty decision-making process is highly variable and dependent on multiple factors. To retain service members (SM) post-injury, there needs to
Riley C. Sheehan   +6 more
doaj   +1 more source

The Ever-Changing Landscape of Informed Consent and Whether the Obligation to Explain a Procedure to the Patient May Be Delegated [PDF]

open access: yes, 2019
Informed consent is an integral part of the shared decision making process and requires a patient be informed of the benefits, risks and alternatives to a medical procedure.
Hodge, Samuel D.   +1 more
core   +2 more sources

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