The impact of the DWI-FLAIR-mismatch in the ECASS-4 trial – A post hoc analysis [PDF]
Abstract Introduction To investigate the impact of a mismatch between diffusion-weighted imaging (DWI) and fluid attenuated inversion recovery (FLAIR) on functional outcome in patients with acute stroke in a prolonged time window or unknown time of symptom onset randomized to intravenous ...
Geoffrey Donnan +2 more
exaly +8 more sources
Simple quantitative measurement based on DWI to objectively judge DWI-FLAIR mismatch in a canine stroke model [PDF]
PURPOSEDiffusion-weighted imaging (DWI) - fluid attenuated inversion recovery (FLAIR) mismatch was proven useful to time the onset of wake-up stroke; however, identifying the status of FLAIR imaging has been mostly subjective.
Sheng Liu +9 more
doaj +5 more sources
DWI-FLAIR Mismatch at MRI Versus Infarct-Penumbra Mismatch on CT Perfusion [PDF]
Margaux Collard +2 more
doaj +6 more sources
COVID-19 Associated Wake-Up Stroke Treated With DWI/FLAIR Mismatch Guided Intravenous Alteplase: A Case Report. [PDF]
Introduction: Wake-up strokes are challenging to manage due to unknown time of onset. Recently, the wake-up trial demonstrated that recombinant tissue plasminogen activator (rtPA) could be administered based on the magnetic resonance imaging (MRI)- diffusion weighted imaging/fluid attenuated inversion recovery mismatch.
Biag E +4 more
europepmc +4 more sources
Predictive value of DWI-FLAIR Mismatch in patients with Ischemic Stroke and receiving Endovascular treatment beyond Time Window. [PDF]
Objective: To investigate the efficacy and safety of endovascular treatment in patients having acute ischemic stroke with over-time window under DWI-FLAIR mismatch. Methods: From January 2018 to January 2020, 80 patients who met the research criteria in the First Central Hospital of Baoding, China were selected.
Cao S, Dong H.
europepmc +4 more sources
Utilization of DWI-FLAIR Mismatch for Intravenous Thrombolysis in an Elderly Patient With Stroke. [PDF]
Objectives To discuss utility of using DWI-FLAIR mismatch in select patients not included in the original WAKE-UP trial for administration of IV thrombolytics. Methods We identified a female over 100 years old who presented with stroke
Ryan D, Chang V, Ouf A.
europepmc +3 more sources
Quantification Beyond Binary of MR FLAIR Hyperintensity Lesions in Acute Ischemic Stroke of Unknown Time Since Onset [PDF]
Background: High inter-rater variability in DWI-FLAIR mismatch assessments for acute ischemic stroke (AIS) has spurred interest in assisting automated imaging measures.
Cecilie Juul Mørck Offersen +7 more
doaj +2 more sources
Favorable Bridging Therapy Based on DWI-FLAIR Mismatch in Patients with Unclear-Onset Stroke. [PDF]
Standard selection criteria for revascularization therapy usually exclude patients with unclear-onset stroke. Our aim was to evaluate the efficacy and safety of revascularization therapy in patients with unclear-onset stroke in the anterior circulation and to identify the predictive factors for favorable clinical outcome.We retrospectively analyzed 41 ...
Mourand I +9 more
europepmc +4 more sources
Automated Assessment of the DWI-FLAIR Mismatch in Patients with Acute Ischemic Stroke: Added Value to Routine Clinical Practice. [PDF]
The DWI-FLAIR mismatch is used to determine thrombolytic eligibility in patients with acute ischemic stroke when the time since stroke onset is unknown. Commercial software packages have been developed for automated DWI-FLAIR classification. We aimed to use e-Stroke software for automated classification of the DWI-FLAIR mismatch in a cohort of patients
Tavakkol E +15 more
europepmc +3 more sources
O-001 DWI-FLAIR mismatch does not predict time of stroke onset in DEFUSE 3 patients [PDF]
Introduction Acute stroke patients with unclear time of symptom onset have traditionally been ineligible for treatment with IV tissue plasminogen activator (tPA) based on a strict time window of treatment within 4.5 hours of symptom onset. Recently, the use of DWI-FLAIR mismatch to identify patients within the 4.5 hour time window has been suggested ...
Robin Lemmens, M Marks, J Heit
exaly +2 more sources

