Results 61 to 70 of about 1,775 (137)

Cerebral Infarction: Epidemiology, Classification, Mechanisms, Diagnosis, and Management

MedComm, Volume 7, Issue 4, April 2026.
Within minutes after ischemia onset, deprivation of oxygen and glucose leads to rapid ATP depletion, resulting in failure of Na+/K+‐ATPase activity and membrane depolarization. This ionic imbalance promotes uncontrolled synaptic release of glutamate and excessive activation of postsynaptic NMDA and AMPA receptors.
Meibiao Zhang, Jianxun Hou, Jia Kuang, Lei Hao, Zhao Yang   +4 more
wiley   +1 more source

Wake-up stroke: clinical characteristics, imaging findings, and treatment option – an update.

Frontiers in Neurology, 2014
About 25% of all strokes occur during sleep, i.e. without knowledge of exact time of symptom onset. According to licensing criteria, this large group of patients is excluded from treatment with rt-PA, the only specific stroke treatment proven effective ...
David eRimmele, Götz eThomalla
doaj   +1 more source

Assessment of pTERT Subtypes of Glioblastoma by Quantitative FLAIR Analysis Based on Fusing MRI Images

Brain and Behavior, Volume 16, Issue 3, March 2026.
Assessment of pTERT subtypes of glioblastoma by quantitative FLAIR analysis based on fusing MRI images, Participants, Methods, Results, Glioblastoma patients, Segmented to 3 subregions Investigated the significant metrics of subregions and other clinical‐imaging factors Prediction models of pTERT Tested in validation cohorts pTERTm, pTERTw, Conclusion:
Bocong Gao, Guanmin Quan, Yawu Liu, Tao Yuan   +3 more
wiley   +1 more source

Large vessel occlusion mediated fluid attenuated inversion recovery signal intensity ratio is associated with stroke within 4.5 h

Frontiers in Neurology
IntroductionThe primary objective was to investigate the value of the fluid attenuated inversion recovery (FLAIR) signal intensity ratio (SIR) in identifying stroke within 4.5 h.
Yajing Wang, Qianqian Mao, Liang Jiang, Mingyang Peng, Yu-Chen Chen, Hong Zhang, Liwei Wang, Xindao Yin   +7 more
doaj   +1 more source

Radiogenomics: Current Understandings and Future Perspectives

MedComm, Volume 7, Issue 2, February 2026.
Radiogenomics links imaging phenotypes with genetic variations, offering potential for comprehensive understanding, cost‐effective diagnosis, and prognosis prediction to advance personalized medicine. However, its clinical application remains limited by several challenges.
Xinyu Zhang, Qingpei Lai, Jin Cao, Jerry Chi Fung Ching, Xinzhi Teng, Jiang Zhang, Shara Wee Yee Lee, Ge Ren, Jing Cai   +8 more
wiley   +1 more source

“Time Is Brain” – for Cell Therapies

Advanced Science, Volume 13, Issue 6, 30 January 2026.
The concept that “time is brain” extends to stem cell therapy for stroke. Evidence across preclinical and clinical studies indicates that delivery timing shapes graft survival, integration, and efficacy by matching the evolving post‐stroke microenvironment.
Hao Yin, Dominikus Brian, Rebecca Z. Weber, Patrick D. Lyden, Ruslan Rust   +4 more
wiley   +1 more source

Accelerated visual recovery from protracted hypoxic cortical blindness in a child

American Journal of Ophthalmology Case Reports, 2019
Purpose: This report describes accelerated visual recovery in a child following protracted hypoxic cortical visual loss and reviews mechanisms responsible for visual recovery.
Sasha Mansukhani, Mai-Lan Ho, Elizabeth A. Bradley, Michael C. Brodsky   +3 more
doaj   +1 more source

Brain MRI Radiomic First‐Order Features for Presurgical Prediction of Meningioma Grading

Journal of Neuroimaging, Volume 36, Issue 1, January/February 2026.
ABSTRACT Background and Purpose Grading meningioma guides treatment choices from follow‐up to surgical resection with adjuvant radiation. Radiomics may offer a non‐invasive alternative to biopsies. We assessed radiomic features (RFs) for distinguishing Grade 1 and Grade 2 meningiomas on preoperative multiparametric MRI. Methods Presurgical T1‐weighted (
Camilo Pineda‐Ibarra, Josep Puig, Diego Nuñez‐Leiva, Yensa Rodríguez, Juan Mora, Santiago Medrano‐Martorell, Jose Carlos Pariente, Marc Comas‐Cufí, Aida Niñerola‐Baizán, Arnau Farré‐Melero, Daniel Alejandro Reyes‐Barrios, Iban Aldecoa, Laura Oleaga, Sofia González‐Ortiz   +13 more
wiley   +1 more source

Are Big Prostates a Challenge? Correlation Between Prostate Volume and Detection Rate in Fusion Biopsy of the Prostate

Advances in Urology, Volume 2026, Issue 1, 2026.
Background This study investigates the relationship between prostate cancer (PCa) detection rates and prostate volume. Prostate volume may influence the diagnostic performance of MRI–ultrasound (MRI–US) fusion biopsy. Enlarged prostate glands present specific challenges, including reduced specificity of prostate‐specific antigen (PSA), anatomical ...
Toni Franz, Tom Sicker, Julian Lueke, Benny Dinh, Christoph Breininger, Theodore Spinos, Evangelos Liatsikos, Jens-Uwe Stolzenburg, Sreeja Dattachoudhury   +8 more
wiley   +1 more source

A Real-world Study of MRI-guided Intravenous Thrombolytic Therapy in Acute Ischemic Stroke [PDF]

Zhongguo quanke yixue
Background Ischemic stroke has a high rate of disability and mortality, and for some patients, the onset time is difficult to confirm, making treatment for these patients particularly important. Objective To explore the efficacy and safety of intravenous
TAN Yi, ZHU Lihong, YIN Zengwei, HOU Shunan, YU Houming
doaj   +1 more source