Results 61 to 70 of about 76,947 (266)

HD‐tDCS Restores Perivascular AQP4 Polarization via PPARγ Modulation to Enhance Glymphatic Clearance After Intracerebral Hemorrhage in Mice

Advanced Science, EarlyView.
HD‐tDCS promotes recovery after intracerebral hemorrhage by enhancing PPARγ‐dependent astrocyte remodeling in a mouse model of ICH. This process suppresses proinflammatory astrocytic activation, restores perivascular AQP4 repolarization, and improves glymphatic influx and efflux, thereby facilitating hematoma and perihematomal edema clearance and ...
Zhiming Li, Yingmei Zhang, Qianqian Tong, Zhitao Gong, Shanyu Zhang, Zhen Qian, Hui Zhang, Qian Yao, Qi Li   +8 more
wiley   +1 more source

Role of Diagnostic Accuracy of Diffusion-Weighted Imaging In Adult Posterior Fossa Tumors – A Prospective Cross-Sectional Study

Journal of Pharmacy and Bioallied Sciences
Aim: This study aims to investigate the role of diffusion-weighted imaging (DWI) in enhancing the diagnostic accuracy of adult posterior fossa tumors.
B Keerthana, M Janani Moorthy, R Sarvesh, Vinoth Thangam   +3 more
doaj   +1 more source

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang, Wenhao Ma, Yi Zhou, Zhijie Wu, Pan Gao, Hongze Niu, Hongfei Tai, Tianyi Zhao, Zheyue Dong, Li Li, Yan Zhang, An Wang, Si Shen, Yueyang Li, Sifei Yu, Yan Peng, Wang Sheng, Xiaoyan Dong, Hua Pan, Kaibin Shi, Magdalena J. Koziol, Xiaobing Wu, Zaiqiang Zhang   +22 more
wiley   +1 more source

Features of Evaluating Renal Diffusion-Weighted Images and ASL-Perfusion Results in Acute Kidney Injury

Вестник рентгенологии и радиологии
Objective: to evaluate the features of renal diffusion-weighted images (DWI) and arterial spin labeling (ASL) perfusion results in acute kidney injury (AKI).Material and methods. In the intensive care unit of Clinical Hospital No.
Yu. Yu. Shkuratov, T. G. Morozova
doaj   +1 more source

Current Status and Challenges of Imaging‐Based Diagnosis of Lymph Node Metastasis in Colon Cancer: The Lymph Node Committee of the Japanese Society for Cancer of the Colon and Rectum

Annals of Gastroenterological Surgery, EarlyView.
This review of the status and challenges of diagnosis of lymph node metastasis in colon cancer suggests that it is currently difficult to establish strict criteria for lymph node metastasis, indicating only moderate diagnostic performance. ABSTRACT Background Accurate pre‐treatment evaluation of lymph node metastasis (LNM) in colon cancer is important ...
Shimpei Ogawa, Yuji Takayama, Yasuyuki Takamizawa, Yukihide Kanemitsu, Hideki Ueno   +4 more
wiley   +1 more source

The Case of an 18‐Year‐Old Female With Persistent Vague Pain in the Top of the Occiput

Annals of Clinical and Translational Neurology, EarlyView.
Jianping Zhong, Binglin Lai
wiley   +1 more source

Severe ADEM‐Like Neuroinflammatory Disease and Cerebrovascular Fragility With Recurrent Pseudoaneurysms and Moyamoya in a Familial Germline CBL Mutation: Expanding the Clinical Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Heterozygous germline variants in CBL disrupt its function as a negative regulator of the Ras/MAPK pathway, classically predisposing to Juvenile myelomonocytic leukemia (JMML) and moyamoya. We describe two affected siblings carrying a paternally inherited CBL variant (c.1210 T> C, p.
Michal Bar‐Hakim, Anat Abramovich, Sara Via‐Dorembus, Gali Heimer, Bruria Ben‐Zeev, Etai Adam, Assaf A. Barg, Jonathan Roth, Basheer Sheick‐Yousif, Rony Beeri Berkowiz, Michal Feldon, Haim Bassan, Moran Hausman‐Kedem   +12 more
wiley   +1 more source

A study on diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging combined with diffusion-weighted imaging in patients with prostate cancer [PDF]

Journal of Men's Health
Background: This study aims to evaluate the diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), diffusion-weighted imaging (DWI), and their combination in prostate cancer patients.
Lili Ying, Kaiyan Hu, Haifeng Qiu, Lingling Ying   +3 more
doaj   +1 more source

Scoping literature review: Comparing MRI tractography methods for optic radiation analysis

The Anatomical Record, EarlyView.
Abstract Accurate tractography mapping of the optic radiations is essential to avoiding post‐operative visual field deficits in patients undergoing temporal lobe surgery. This literature review highlights the current landscape of MRI tractography methods that are used to delineate the optic radiations (ORs), with a particular focus on the anterior ...
Hriday Sahni, Cristina Schaurich, Lara Boyd, Claudia Krebs   +3 more
wiley   +1 more source

The role of diffusion-weighted MRI in the evaluation of imaging for prostate carcinoma: A systematic review

MGM Journal of Medical Sciences
Background: Prostate cancer is one of the most common cancers in men. In recent times, diffusion-weighted imaging (DWI) sequence magnetic resonance imaging (MRI) techniques have been used in the diagnosis of prostate cancer. The present systematic review
Komal Mishra, Asish Pavanan, Pratapsingh Hanumansingh Parihar   +2 more
doaj   +1 more source