Results 61 to 70 of about 324,214 (307)

Ultra‐Radiostable Covalent Conformationally Interlocked Networks Enabling a Universal Radiometal‐Labeling Platform for Cancer Radioembolization

Advanced Science, EarlyView.
Conjugated poly(imide dioxime)‐based microspheres establish a radiometal coordination‐driven conformational interlocked network with ultra‐high radiostability. This platform enables low‐temperature, multi‐radionuclide labeling for SPECT/PET/MRI imaging and radionuclide therapy. Mechanistic insights from EXAFS and DFT reveal enhanced stability, while in
Xiao Xu, Zhenwen Zhao, Yangjie Wang, Zhigang Liu, Zhijie Liu, Xiaoling Li, Zhichen Mao, Lu Xu, Gan Lin, Gang Liu, Hongjuan Ma   +10 more
wiley   +1 more source

A study on diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging combined with diffusion-weighted imaging in patients with prostate cancer [PDF]

Journal of Men's Health
Background: This study aims to evaluate the diagnostic efficacy of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI), diffusion-weighted imaging (DWI), and their combination in prostate cancer patients.
Lili Ying, Kaiyan Hu, Haifeng Qiu, Lingling Ying   +3 more
doaj   +1 more source

Mechano‐Nanoswitches for Ultrasound‐Controlled Drug Activation

Advanced Science, 2022
Current pharmacotherapy is challenged by side effects and drug resistance issues due to the lack of drug selectivity. Mechanochemistry‐based strategies provide new avenues to overcome the related problems by improving drug selectivity.
Shuaidong Huo, Zhihuan Liao, Pengkun Zhao, Yu Zhou, Robert Göstl, Andreas Herrmann   +5 more
doaj   +1 more source

Toward Material‐Specific Peptides From in Silico Guided Peptide Engineering to Target PET in the Presence of PS

Advanced Science, EarlyView.
This work presents a computational–experimental strategy to engineer material‐binding peptides toward polymer specificity. Molecular dynamics simulations identified residues driving polystyrene binding, enabling targeted substitutions that greatly reduced polystyrene affinity while preserving PET binding.
Julian Luka, Marian Bienstein, Jonas Berger, Ulrich Schwaneberg   +3 more
wiley   +1 more source

Implementasi Program Jaminan Kesehatan Khusus Terpadu dalam Upaya Perlindungan dan Pemenuhan Hak Kesehatan Penyandang Disabilitas

Journal of Social Development Studies, 2021
Program Jamkesus Terpadu digulirkan oleh Pemerintah Daerah DIY melalui Bapel Jamkesos DIY untuk mewujudkan perlindungan dan pemenuhan hak kesehatan penyandang disabilitas dengan cara mempermudah, mendekatkan, memfasilitasi, dan memberikan jaminan ...
Rut Dwi Ardiyantini
doaj   +1 more source

Mechanochemical Activation of a Bridged‐Exciplex Optical Force Probe

Advanced Science, EarlyView.
A bridged‐exciplex optical force probe is synthesized, switching from solvatochromic charge‐transfer emission in the latent state to intense locally excited emission upon activation. This dual photophysical response with additional changes in quantum yield and fluorescence lifetime enables precise environmental sensing and distinct optical readouts ...
Ronja Schumann, Andreas Bock, Felix Majer, Michael Baumann, Michael Olney‐Fraser, Lev Kazak, Fedor Jelezko, Alexander J. C. Kuehne, Robert Göstl   +8 more
wiley   +1 more source

Value of DWI- ADC and FUSION T2-DWI in the management of oncological patients [PDF]

Cancer Imaging, 2015
Content organisation The detection and characterisation of malignant lesions can often be difficult, principally when the disease is small or when the tumour is combined with normal tissues. Forty five patients with malignancies underwent both DWI MRI and T2-DWI to detect and characterise primary and metastatic tumours. We acquired DWI (b0, b400, b600),
Nazar, M, Saguier, F, Alarcon, L, Pascuzzi, M, Wirtz, M, Eyheremendy, E   +5 more
openaire   +1 more source

AI‐Assisted Tumor Boundary Delineation via Targeted Ultrasmall Iron Oxide Nanoprobe for High‐Contrast HER2‐Positive Tumor Imaging

Advanced Science, EarlyView.
A novel targeted and pH‐responsive MRI contrast agent was integrated with a 3D nnU‐Net deep learning framework to enable accurate delineation of tumor boundary morphology in HER2‐positive breast cancer imaging. ABSTRACT Breast cancer continues to be a leading cause of cancer‐related mortality in women globally, where precise diagnosis and clear tumor ...
Jiaying Zheng, Yi Zhu, Xinrui Li, Sunxian Dai, Xiangyuan Ma, Hongwei Lu, Zhongling Wang, Benqing Zhou   +7 more
wiley   +1 more source

Longitudinal Multifrequency MR Elastography Reveals Biomechanical Signatures of Progression in a Translational Liver Tumor Model

Advanced Science, EarlyView.
Longitudinal multifrequency magnetic resonance elastography (mMRE) performed on a clinical 3 Tesla magnetic resonance imaging system reveals early biomechanical alterations during liver tumor progression in a translational VX2 model. Changes in tumor stiffness and viscosity precede diffusion‐related alterations and are associated with extracellular ...
Justus Ramtke, Friederike Hesse, Lasse Noack, Justus Klockner, Yubei He, Yu Liu, Yanglei Wu, Robin Schmidt, Selma Saclier, Salma A. S. Abosabie, Tom Meyer, Richard Ruppel, Nikolaus Berndt, Michael Mülleder, Eyk Schellenberger, Nicola Beindorff, Dominik N. Müller, Ingolf Sack, Jing Guo, Shraga Nahum Goldberg, Lynn Jeanette Savic   +20 more
wiley   +1 more source

Automated DWI-FLAIR mismatch assessment in stroke using DWI only

European Stroke Journal
Abstract Introduction In Acute Ischemic Stroke (AIS), mismatch between Diffusion-Weighted Imaging (DWI) and Fluid-Attenuated Inversion-Recovery (FLAIR) helps identify patients who can benefit from thrombolysis when stroke onset time is unknown (15% of AIS).
Benzakoun, Joseph, Scheldeman, Lauranne, Wouters, Anke, Cheng, Bastian, Ebinger, Martin, Endres, Matthias, B Fiebach, Jochen, Fiehler, Jens, Galinovic, Ivana, W Muir, Keith, Nighoghossian, Norbert, Pedraza, Salvador, Puig, Josep, Z Simonsen, Claus, Thijs, Vincent, Thomalla, Götz, Micard, Emilien, Chen, Bailiang, Lapergue, Bertrand, Boulouis, Grégoire, Le Berre, Alice, Baron, Jean-Claude, Turc, Guillaume, Ben Hassen, Wagih, Naggara, Olivier, Oppenheim, Catherine, Lemmens, Robin   +26 more
openaire   +8 more sources