Results 141 to 150 of about 6,069 (180)
Some of the next articles are maybe not open access.
Digitale Radiogrammetrie (DXR)
Monatsschrift Fur Kinderheilkunde, 2007A Malich, H -J Mentzel, A Pfeil
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International Journal of Oncology, 1993
To establish a rapid, specific, sensitive and simple assay method for doxorubicin (DXR) in body fluid, monoclonal antibodies (MAbs) against DXR were generated by immunizing mice with keyhole limpet hemocyanin-DXR conjugate, cell fusion, and a one step, time saving screening ELISA method using aminoplate-coupled DXR via a glutaraldehyde bridge as solid ...
K, Ohkawa +4 more
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To establish a rapid, specific, sensitive and simple assay method for doxorubicin (DXR) in body fluid, monoclonal antibodies (MAbs) against DXR were generated by immunizing mice with keyhole limpet hemocyanin-DXR conjugate, cell fusion, and a one step, time saving screening ELISA method using aminoplate-coupled DXR via a glutaraldehyde bridge as solid ...
K, Ohkawa +4 more
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ACM SIGCOMM Computer Communication Review, 2012
Can a software routing implementation compete in a field generally reserved for specialized lookup hardware? This paper presents DXR, an IPv4 lookup scheme based on transforming large routing tables into compact lookup structures which easily fit into cache hierarchies of modern CPUs.
Marko Zec, RIZZO, LUIGI, Miljenko Mikuc
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Can a software routing implementation compete in a field generally reserved for specialized lookup hardware? This paper presents DXR, an IPv4 lookup scheme based on transforming large routing tables into compact lookup structures which easily fit into cache hierarchies of modern CPUs.
Marko Zec, RIZZO, LUIGI, Miljenko Mikuc
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A computational study of the molecular basis of antibiotic resistance in a DXR mutant
Journal of Computer-Aided Molecular Design, 2019Proteins of the independent mevalonate pathway for isoprenoid biosynthesis are important targets for the development of new antibacterial compounds as this pathway is present in most pathogenic organisms such as Mycobacterium tuberculosis, DPlasmodium falciparum and Escherichia coli, but is not present in mammalian species, including humans.
Roland H Stote
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Anti-Cancer Drugs, 1996
After treatment of AH66DR cells with the multidrug resistance (MDR) phenotype with bovine serum albumin (BSA)-conjugated [14C]doxorubicin (DXR), accumulation of the drug in the secondary lysosomal fraction increased as a function of time up to 24 h without any significant increase of the drug in other organellae.
N, Takahashi, T, Asakura, K, Ohkawa
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After treatment of AH66DR cells with the multidrug resistance (MDR) phenotype with bovine serum albumin (BSA)-conjugated [14C]doxorubicin (DXR), accumulation of the drug in the secondary lysosomal fraction increased as a function of time up to 24 h without any significant increase of the drug in other organellae.
N, Takahashi, T, Asakura, K, Ohkawa
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Reverse Fosmidomycin Derivatives against the Antimalarial Drug Target IspC (Dxr)
Journal of Medicinal Chemistry, 2011Reverse hydroxamate-based inhibitors of IspC, a key enzyme of the non-mevalonate pathway of isoprenoid biosynthesis and a validated antimalarial target, were synthesized and biologically evaluated. The binding mode of one derivative in complex with EcIspC and a divalent metal ion was clarified by X-ray analysis.
Behrendt, Christoph T. +13 more
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Bioorganic & Medicinal Chemistry, 2011
The diethyl esters and disodium salts of a range of heteroarylcarbamoylphosphonic acids have been prepared and evaluated as analogues of the highly active DOXP-reductoisomerase (DXR) inhibitor, fosmidomycin. Computer-simulated docking studies, Saturation Transfer Difference (STD) NMR analysis and enzyme inhibition assays have been used to explore ...
Bodill, Taryn +4 more
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The diethyl esters and disodium salts of a range of heteroarylcarbamoylphosphonic acids have been prepared and evaluated as analogues of the highly active DOXP-reductoisomerase (DXR) inhibitor, fosmidomycin. Computer-simulated docking studies, Saturation Transfer Difference (STD) NMR analysis and enzyme inhibition assays have been used to explore ...
Bodill, Taryn +4 more
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International Journal of Pharmaceutics, 2006
We have reported that targeted, pH-sensitive sterically stabilized liposomes are able to increase the cytotoxicity of DXR in vitro against B lymphoma cells, but the rate of release of DXR in plasma was too rapid to permit the results to be extended to in vivo applications. The purpose of the study reported here is two-fold.
Tatsuhiro, Ishida +3 more
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We have reported that targeted, pH-sensitive sterically stabilized liposomes are able to increase the cytotoxicity of DXR in vitro against B lymphoma cells, but the rate of release of DXR in plasma was too rapid to permit the results to be extended to in vivo applications. The purpose of the study reported here is two-fold.
Tatsuhiro, Ishida +3 more
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±DXr Enklitiğinin Odaklayıcı İşlevi
Dil AraştırmalarıBu makalede, Bütün adayı bir kuş cıvıltısıdır alır (FSKAB, 83), Bir patırdıdır gidiyor (SK II, 549), İşte bir kazadır oldu (K, 156), Yine bir gülmedir tutturdular (KT, 95) gibi cümlelerde kullanılan ve bir kiplik işaretleyicisi olarak ele aldığımız ±DXr enklitiğinin “odaklayıcılık” işlevi üzerinde durulmaktadır.
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