Results 71 to 80 of about 850,427 (314)

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Bioactive and biodegradable cotton fabrics produced via synergic effect of plant extracts and essential oils in chitosan coating system

Scientific Reports
Functional antibacterial textile materials are in great demand in the medical sector. In this paper, we propose a facile, eco-friendly approach to the design of antibacterial biodegradable cotton fabrics.
Bolesław Szadkowski, Magdalena Śliwka-Kaszyńska, Anna Marzec   +2 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Dye-labeled B₇ probes. [PDF]

, 2019
(A) Biotin-4-fluorescein (BFl) contains a shorter spacer of 10 non-hydrogen atoms between the bicyclic ring and the dye structure. (B) Oregon green 488 Biocytin (BcO) has a spacer of 20 non-hydrogen atoms between the bicyclic ring and the fluorescent dye.
Katie A. Carnes (6411725), Timothy C. Mueser (5448011), José González-Valdez (6411728), Lawrence J. Parkhurst (61526), Kathia Zaleta-Rivera (1334064), Roberto F. Delgadillo (843498)   +5 more
core   +1 more source

John Dye to R.H. Prewitt [PDF]

Dye and his wife send their congratulations to Prewitt and his new wife.Prewitt, R.H.1860s (1860-1869)Indianapolis (Ind.)600ppiCivil War Home FrontDC045This Civil War Home Front collection was funded by ...
Dye, John
core   +4 more sources

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Dye-Sensitized Downconversion [PDF]

, 2018
Splitting one high-energy photon into two lower energy photons through downconversion has been demonstrated for a variety of combinations of rare earth (RE) ions.
Andries Meijerink (1469017), Meijerink, Andries, Condensed Matter and Interfaces, Zijun Wang, Zijun Wang (1387710), Andries Meijerink, Wang, Zijun, Sub Condensed Matter and Interfaces   +7 more
core   +1 more source

Antioxidant Potential of Hydroxycinnamic Acids in Advanced Oxidation Processes

International Journal of Electrochemical Science, 2016
The aim of the study was to describe the characteristics of a natural antioxidant derived from the group of the hydroxycinnamic acids (sinapic and ferulic acid). Electrochemical methods and other spectrophotometric assays were studied for the analysis to
Anna Masek, Ewa Chrzescijanska, Malgorzata Latos, Marian Zaborski   +3 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source