Results 31 to 40 of about 8,248 (263)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
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TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series C, 1991 The dynamic vibration absorbers consist of a mass and a viscoelastic element. As the mechanical models of the viscoelastic absorber element, the Voigt model, the Maxwell model and the three-element model are employed. The Voigt model is identical to the viscoeelastic element for the conventional dynamic absorbers.
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An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
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Dynamic absorber for ropeway gondola using Coriolis force
Vietnam Journal of Mechanics, 2008 Wind-induced swinging of ropeway gondola can be reduced using dynamic absorbers. To maximize the performance of conventional dynamic absorbers, their location should be as high as possible. However, absorbers can not be installed at high positions due to
Hiroshi Matsuhisa, Masashi Yasuda
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Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
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PLoS ONEThe design parameters of the dynamic vibration absorber significantly affect the motion performance of the main vibration system. The Brock's approaching zero method was improved as approaching the fixed point frequency method.
Hongliang Tian, Xixiao Liang, Xuan Du
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Design and Mechanical Properties Test of Double Dynamic Vibration Absorber forHigh-temperature Pipelines [PDF]
Zhengzhou Daxue xuebao. Gongxue banIn view of the fact that it was difficult to solve the problem of irregular vibration of small and mediumsized branch pipes in nuclear power units with traditional vibration damping supports, a circular double three-waydynamic vibration absorber based ...
BAI Hongbai +3 more
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Beamlike dynamic vibration absorbers [PDF]
The Journal of the Acoustical Society of America, 1981 Although the concept of the dynamic absorber and its potential for vibration reduction were first discussed in the early part of this century, John Snowdon's comprehensive work in this area was certainly a pioneering effort. By rephrasing the standard equations in terms of complex dynamic moduli, it became possible to treat viscoelastic (rubberlike ...
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FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
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