Results 51 to 60 of about 2,147 (259)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Firm Dynamics and Pricing Under Customer Capital Accumulation [PDF]
SSRN Electronic Journal, 2018 Abstract In a search model of firm dynamics, customer accumulation is shown to affect the lifecycle of firms and the dynamics of markups in response to aggregate demand shocks. In the model, sellers of different sizes and productivities post dynamic pricing contracts to strike a balance between attracting new customers and exploiting pre-existing ...
Pau Roldan-Blanco, Sonia Gilbukh
openaire +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Dynamic equations for nonassociated gas accumulation
Petroleum Exploration and Development, 2008 Nonassociated gas can be classified as conventional gas accumulation with displacement migration, source-contacting gas accumulation with piston-type migration, and shale gas accumulation with the displacement and piston-type migrations. Nonassociated gas accumulation can be described by using the continuous but universal dynamic equation.
Jin-chuan ZHANG +6 more
openaire +2 more sources
Dynamic 3D Scene Analysis by Point Cloud Accumulation
, 2022 Multi-beam LiDAR sensors, as used on autonomous vehicles and mobile robots, acquire sequences of 3D range scans ("frames"). Each frame covers the scene sparsely, due to limited angular scanning resolution and occlusion. The sparsity restricts the performance of downstream processes like semantic segmentation or surface reconstruction. Luckily, when the
Huang, Shengyu +4 more
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Chemical Engineering Transactions, 2019 This study highlights the CO2e - emission reduction potentials and related economic consequences for changing the steam generation from fossil to renewable.
Ron-Hendrik Peesel +2 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source