Results 81 to 90 of about 4,620,298 (319)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Context-aware Authorization in Highly Dynamic Environments

, 2009
Highly dynamic computing environments, like ubiquitous and pervasive computing environments, require frequent adaptation of applications. Context is a key to adapt suiting user needs. On the other hand, standard access control trusts users once they have
Hourdin, Vincent, REY, Gaetan, LAVIROTTE, Stephane, RIVEILL, Michel, TIGLI, Jean-Yves   +4 more
core  

IPv6 Network Mobility [PDF]

, 2007
Network Authentication, Authorization, and Accounting has been used since before the days of the Internet as we know it today. Authentication asks the question, “Who or what are you?” Authorization asks, “What are you allowed to do?” And fi nally ...
Soto Campos, Ignacio, Soto, Ignacio, Bernardos, Carlos J., Bernardos Cano, Carlos Jesús, Calderón Pastor, María Carmen, Calderón, María   +5 more
core  

A Blockchain-Based Trustworthy Access Control Scheme for Medical Data Sharing

IET Information Security
Blockchain is commonly employed in access control to provide safe medical data exchange because of the characteristics of decentralization, nontamperability, and traceability.
Canling Wang, Wei Wu, Fulong Chen, Hong Shu, Ji Zhang, Yuxuan Zhang, Taochun Wang, Dong Xie, Chuanxin Zhao   +8 more
doaj   +1 more source

Authoring and Dynamic Generation of Adaptive E-courses [PDF]

, 2004
Adaptive hypermedia constitutes a pretty rich resource for developing web-based courses. With the aim of dynamically generating adaptive e-courses, we have developed the TANGOW system which, starting from the course components and their adaptation capabilities (specified independently and out of the adaptation engine), generates different courses for ...
Rosa M. Carro, Manuel Freire 0001, Estefanía Martín 0001, Alvaro Ortigosa, Pedro Paredes 0001, Pilar Rodríguez 0001, Johann H. Schlichter   +6 more
openaire   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Adding Support to XACML for Multi-Domain User to User Dynamic Delegation of Authority [PDF]

, 2009
. We describe adding support for dynamic delegation of authority between users in multiple administrative domains, to the XACML model for authorisation decision making.
Otenko, Sassa, Chadwick, David W., Nguyen, Tuan Anh   +2 more
core   +1 more source

From consent to authorization

Etikk i Praksis: Nordic Journal of Applied Ethics
The turn from traditional paternalism and towards patient autonomy has made informed consent a key concept for medical ethics and health legislation.
Bjørn Hofmann
doaj   +1 more source

Biophysical approaches for studying viral entry

FEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Autorização de serviços com garantias de QoS baseada em perfis de usuário [PDF]

, 2008
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Ciência da Computação.Vários trabalhos recentes propõem soluções de QoS permitindo que os usuários especifiquem explicitamente a qualidade ...
Royer, Julio César
core