Results 121 to 130 of about 2,039,028 (336)

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

A validation of mobile sensing actigraphy devices for generating a biomechanical model of posture [PDF]

open access: yes, 2017
Mobile sensing actigraphy was tested and validated as a modality for computing dynamic posturography. Twelve healthy volunteer subjects (6 male) were administered risperidone and assessed for postural stability using a NeuroCom® Balance Master system and
Detheridge, Craig Neal
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Comparison of the Effect of Insole with Different Widgets on Static and Dynamic Balance

open access: yesپزشکی بالینی ابن سینا, 2020
Background and Objective: Improving control of balance is essential for carrying out daily activities of life as a basic functional ability. The importance role of external intervention on the foot balance as main point of contact between land and body ...
Ali Yalfani   +2 more
doaj  

Modelling crediting volume by using the system dynamic method [PDF]

open access: yes
This paper describes a system dynamic model of credit burden, and it provides an estimation of credit volume. The elaborated model calculates and estimates household budget balance and budget forming flows: income and expenditures, loan and interest ...
Skribans, Valerijs
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Stochastic Models Of Dynamic Balance State For The Morphological Patterns Of Cryolithozone Landscapes

open access: yesGeography, Environment, Sustainability, 2019
The paper deals with mathematical modeling of a morphological pattern for a broad spectrum of cryolithozone landscapes in a state of a dynamic balance.
Alexey S. Victorov, Olga N. Trapeznikova
doaj   +1 more source

A Dynamic Factor Analysis of Financial Contagion in Asia [PDF]

open access: yes
In this paper we compared the performance of country specific and regional indicators of reserve adequacy in predicting, out of sample, the balance of payment crisis affecting the South East Asian region during the 1997-98 period. A Dynamic Factor method
Andrea Cipollini, George Kapetanios
core  

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